3-(2,5-dimethylbenzyl)-3-methylpentanoic acid | 228122-68-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 苯丙酸
• 英文名称: 3-(2,5-dimethylbenzyl)-3-methylpentanoic acid
• CAS: 228122-68-7
• 化学式: C₁₅H₂₂O₂
• 分子量: 234.338
• InChiKey: VTNNYYPOTUGHBP-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  3-(2,5-dimethylbenzyl)-3-methylpentanoic acid 在 氯化亚砜 、 PPA 作用下， 以 氯仿 为溶剂， 反应 3.75h， 生成 (E)-3-ethyl-1,2,3,4-tetrahydro-3,5,8-trimethyl-2-thioxonaphthalen-1-one S-(tert-butylimide)
  参考文献：
  名称：

  New Reactions of Thione S-(tert-Alkylimides).

  摘要：

  Two new alpha-chloro sulfenyl chlorides 1, four new 2-thioxo-1-tetralone S-imides 2 (X = CH2), and one new 3-thioxochroman-4-one S-imide 2 (X = O) have been prepared and characterized by comprehensive spectroscopy and, in one case, an X-ray crystal structure determination. Pyrolysis of 2 leads to the corresponding 1,2,4-trithiolanes 3 after extensive sulfur scrambling. Addition of arenethiols to 2 (R-5 = t-Bu), but not 2 (R-5 = 1-adamantyl), leads to the corresponding adducts 13 with an unusual dithioacetal structure. Ozonolysis of 2 gives the corresponding alpha-diketones such as 16.

  DOI：

  10.3891/acta.chem.scand.53-0284
• 作为产物：
  描述：

  3-(2,5-dimethylbenzyl)-3-methylpentanenitrile 在 氢氧化钾 作用下， 以 乙二醇 为溶剂， 反应 6.0h， 以69%的产率得到3-(2,5-dimethylbenzyl)-3-methylpentanoic acid
  参考文献：
  名称：

  New Reactions of Thione S-(tert-Alkylimides).

  摘要：

  Two new alpha-chloro sulfenyl chlorides 1, four new 2-thioxo-1-tetralone S-imides 2 (X = CH2), and one new 3-thioxochroman-4-one S-imide 2 (X = O) have been prepared and characterized by comprehensive spectroscopy and, in one case, an X-ray crystal structure determination. Pyrolysis of 2 leads to the corresponding 1,2,4-trithiolanes 3 after extensive sulfur scrambling. Addition of arenethiols to 2 (R-5 = t-Bu), but not 2 (R-5 = 1-adamantyl), leads to the corresponding adducts 13 with an unusual dithioacetal structure. Ozonolysis of 2 gives the corresponding alpha-diketones such as 16.

  DOI：

  10.3891/acta.chem.scand.53-0284