5-decyl-2-(3-fluoro-4-hydroxyphenyl)pyrimidine | 154162-31-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5-decyl-2-(3-fluoro-4-hydroxyphenyl)pyrimidine
• 英文别名: 2-fluoro-4-(5-decyl-2-pyrimidinyl)phenol；2-Fluoro-4-(5-decylpyrimidine-2-yl)phenol；4-(5-decylpyrimidin-2-yl)-2-fluorophenol
• CAS: 154162-31-9
• 化学式: C₂₀H₂₇FN₂O
• 分子量: 330.446
• InChiKey: USIZGKOAOXXQJF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  24
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  46
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  5-decyl-2-(3-fluoro-4-hydroxyphenyl)pyrimidine 、 反式-4-丙基环己基甲酰氯 以 吡啶 为溶剂， 以60.3%的产率得到2-fluoro-4-(5-decyl-2-pyrimidinyl)phenyl trans-4-n-propylcyclohexylcarboxylate
  参考文献：
  名称：

  Liquid crystal composition and liquid crystal device using same

  摘要：

  公开号：

  EP0401522B1

文献信息

• Fluorine-containing optically active compound and liquid crystal
  申请人：Takasago International Corporation

  公开号：US05275756A1

  公开（公告）日：1994-01-04

  A fluorine-containing optically active compound represented by formula (I): ##STR1## wherein R.sub.1 represents a straight chain alkyl or alkoxy group having from 6 to 14 carbon atoms or a 4-alkylphenyl or 4-alkoxyphenyl group having from 8 to 12 carbon atoms; R.sub.2 represents a straight chain alkyl group having from 1 to 8 carbon atoms; C.sup.* represents an asymmetric carbon atoms; and X represents a hydrogen atom or a fluorine atom, provided that X represents a fluorine atom when R.sub.1 contains a phenyl group, and a liquid crystal composition containing the same are disclosed. The compound (I) has large spontaneous polarization and low viscosity to achieve a fast response time. In the N.sup.* phase of the compound (I), the helical pitch has small temperature dependence.

  公开了一种含氟的光学活性化合物，其化学式为（I）：##STR1## 其中，R.sub.1代表具有6至14个碳原子的直链烷基或烷氧基，或具有8至12个碳原子的4-烷基苯基或4-烷氧基苯基；R.sub.2代表具有1至8个碳原子的直链烷基；C.sup.*代表不对称碳原子；X代表氢原子或氟原子，如果R.sub.1含有苯基，则X代表氟原子。还公开了一种含有该化合物的液晶组合物。化合物（I）具有大的自发极化和低粘度，以实现快速响应时间。在化合物（I）的N.sup.*相中，螺旋周期具有小的温度依赖性。
• Mesomorphic compound, liquid crystal composition, liquid crystal device,
  申请人：Canon Kabushiki Kaisha

  公开号：US05385692A1

  公开（公告）日：1995-01-31

  A mesomorphic compound of the formula (I) according to claim 1 is suitable as a component for liquid crystal composition providing improved response characteristics.

  根据第1项要求，化学式为(I)的介向化合物适用作液晶组分，可提供改善的响应特性。
• Fluorinated pyrimidine-phenyl optically active compounds and liquid crystal compositions thereof
  申请人：Takasago International Corporation

  公开号：EP0469893A1

  公开（公告）日：1992-02-05

  Optically active compounds are represented by the formula: where R₁ is a C6-14 straight chain alkyl or alkoxy group or a C8-12 4-alkylphenyl or 4-alkoxyphenyl group; R₂ is a straight chain C1-9 alkyl group; C* is an asymmetric carbon atom; and X is a hydrogen or fluorine atom, provided that X is fluorine when R₁ contains a phenyl group. 29 such compounds are synthesised and their properties given in Table 1, namely large spontaneous polarization and low viscosity to achieve a fast response time, and in the N* phase of the compound (I), the helical pitch has a small temperature dependence. Liquid crystal compositions contain a compound (I) and can be used as a chiral dopant for an STN or TN mode of liquid crystal element. The compounds can be mixed with compounds which are not optically active and which show a smectic C phase, 23 of which are listed. These compositions are useful in opto-electric elements.

  光学活性化合物由式表示： 其中 R₁ 是 C6-14 直链烷基或烷氧基或 C8-12 4-烷基苯基或 4-烷氧基苯基；R₂ 是直链 C1-9 烷基；C* 是不对称碳原子；X 是氢原子或氟原子，但当 R₁ 含有苯基时，X 为氟原子。合成了 29 种这样的化合物，表 1 给出了它们的特性，即自发极化大、粘度低，以实现快速响应时间，在化合物（I）的 N* 相中，螺旋间距的温度依赖性小。 液晶组合物含有化合物（I），可用作 STN 或 TN 模式液晶元件的手性掺杂剂。这些化合物可与不具有光学活性且呈现出共晶 C 相的化合物混合使用，其中 23 种化合物已经列出。这些化合物可用于光电元件。
• Liquid crystal composition, liquid crystal device, display apparatus and display method
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0460624A2

  公开（公告）日：1991-12-11

  A liquid crystal composition comprising at least one mesomorphic compound represented by the following formula (I): wherein R1 and R2 respectively denote a linear or branched alkyl group having 1 - 16 carbon atoms optionally substituted; Z1 denotes a single bond, -0-, -COO- or -OCO-, X1 denotes halogen; and A1 denotes a single bond or and at least one mesomorphic compound represented by the following formula (II): wherein R3 and R4 respectively denote an alkyl group having 2 - 16 carbon atoms optionally substituted; Y1 denotes a single bond, Z2 and Z3 respectively denote a single bond, -0-, or A2 and A3 respectively denote a single bond, X2 and X3 respectively denote hydrogen, F, Cl, Br, -CH3, -CN or -CF3; and k is 0 or 1 with the proviso that Z2 is a single bond when A2 is a single bond, and Z3 is a single bond when As is a single bond and k is 0. The liquid crystal composition is easily aligned by a simple rubbing method to provide a uniform monodomain and further provides wider driving voltage and temperature margins effective for providing a practical ferroelectric liquid crystal device.

  一种液晶组合物，包含至少一种由以下物质代表的介晶化合物 式（I） 其中 R1 和 R2 分别表示具有 1 - 16 个碳原子的直链或支链烷基，任选被取代；Z1 表示单键、-0-、-COO- 或-OCO-；X1 表示卤素；以及 A1 表示单键或-0-、-COO- 或-OCO-。 以及至少一种由下式（II）代表的中间体化合物： 其中 R3 和 R4 分别表示具有 2-16 个碳原子的烷基，任选被取代；Y1 表示单键、 Z2 和 Z3 分别表示单键、-0-、 或 A2 和 A3 分别表示单键、 X2 和 X3 分别表示氢、F、Cl、Br、-CH3、-CN 或 -CF3；k 为 0 或 1，但当 A2 为单键时，Z2 为单键；当 As 为单键且 k 为 0 时，Z3 为单键。液晶组合物很容易通过简单的摩擦方法对齐，以提供均匀的单域，并进一步提供更宽的驱动电压和温度余量，从而有效地提供实用的铁电液晶器件。
• Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method
  申请人：CANON KABUSHIKI KAISHA

  公开号：EP0546338B1

  公开（公告）日：1998-02-04