N-methyl-4-propylcyclohexan-1-amine | 1042584-67-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-methyl-4-propylcyclohexan-1-amine
• CAS: 1042584-67-7
• 化学式: C₁₀H₂₁N
• mdl: MFCD11156949
• 分子量: 155.28
• InChiKey: BULVHXOJKBLEDC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF
  申请人：Qingdao KingAgroot Chemical Compound Co., Ltd.

  公开号：EP3892618A1

  公开（公告）日：2021-10-13

  The invention belongs to the technical field of pesticides, and specifically relates to a 4-pyridinyl formamide compound or a derivative thereof, a preparation method therefor, a herbicidal composition and the use thereof. The 4-pyridinyl formamide compound is as represented by formula (I), wherein, X and Y each independently represent nitro, halogen, cyano, formyl, thiocyano, mercapto, etc.; and M represents an unsubstituted or substituted structure (II). The compound, and the derivative and the composition thereof have excellent herbicidal activity and a higher crop safety, and establish good selectivity, especially for key crops such as wheat and rice.

  本发明属于农药技术领域，具体涉及一种4-吡啶基甲酰胺化合物或其衍生物、其制备方法、除草组合物及其用途。4-吡啶基甲酰胺化合物由式（I）表示，其中，X 和 Y 各自独立地代表硝基、卤素、氰基、甲酰基、硫氰基、巯基等；M 代表未取代或取代的结构（II）。该化合物及其衍生物和组合物具有优异的除草活性和更高的作物安全性，并建立了良好的选择性，尤其适用于小麦和水稻等主要作物。
• Dianilinopyrimidine compound for inhibiting kinase activity
  申请人：Shenzhen Targetrx, Inc.

  公开号：US11254696B2

  公开（公告）日：2022-02-22

  Disclosed are a dianilino pyrimidine compound having an inhibitory effect on protein tyrosine kinase, pharmaceutically acceptable salts, crystal forms, prodrugs, metabolites, hydrates, solvates, stereoisomers or isotopic derivatives thereof, a pharmaceutical composition containing these compounds, as well as preparation and use of these compounds. The compound has a structure as represented by formula (I), and may be used for treating ALK-mediated cancer-related symptoms, such as non-small cell lung cancer, breast cancer, nerve tumors, esophagus cancer, soft tissue cancer, lymphoma, or leukemia.

  本发明公开了一种对蛋白酪氨酸激酶具有抑制作用的二苯胺基嘧啶化合物、其药学上可接受的盐、晶体形式、原药、代谢物、水合物、溶解物、立体异构体或同位素衍生物、含有这些化合物的药物组合物以及这些化合物的制备和使用方法。该化合物具有式（I）所代表的结构，可用于治疗ALK介导的癌症相关症状，如非小细胞肺癌、乳腺癌、神经肿瘤、食道癌、软组织癌、淋巴瘤或白血病。
• [EN] 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF<br/>[FR] COMPOSÉ 4-PYRIDINYLE FORMAMIDE OU DÉRIVÉ DE CELUI-CI, PROCÉDÉ DE PRÉPARATION CORRESPONDANT, COMPOSITION HERBICIDE ET UTILISATION ASSOCIÉES<br/>[ZH] 4-吡啶基甲酰胺类化合物或其衍生物、制备方法、除草组合物和应用
  申请人：QINGDAO KINGAGROOT CHEMICAL COMPOUND CO LTD

  公开号：WO2020147705A1

  公开（公告）日：2020-07-23

  本发明属于农药技术领域，具体涉及一种4-吡啶基甲酰胺类化合物或其衍生物、制备方法、除草组合物和应用。所述的4-吡啶基甲酰胺类化合物如式（Ⅰ）所示，其中，X、Y分别独立地代表硝基，卤素，氰基，甲酰基，硫氰基，巯基等；M代表未取代或取代的结构（II），所述化合物及其衍生物、组合物的除草活性优异，且具有更高的作物安全性，尤其是对于小麦、水稻等关键农作物建立了良好的选择性。
• DENDRITIC POLYMERS AND MAGNETIC RESONANCE IMAGING CONTRAST AGENT EMPLOYING THE SAME
  申请人：Thirumalai Dhakshanamurthy

  公开号：US20090169481A1

  公开（公告）日：2009-07-02

  A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L) i ) j or SP-DX-Z-L) i ) j , wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is and 1 is not less than 1; D is a C 3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C 3-30 moiety having bi-functional groups; Z is a C 3-20 moiety having a plurality of functional group; and L is a metal cation.
• 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF
  申请人：CHEMO RESEARCH, S.L.

  公开号：US20160257661A1

  公开（公告）日：2016-09-08

  The invention relates to a process for the synthesis of Cariprazine, an antipsychotic compound useful in the treatment of positive and negative symptoms associated to schizophrenia, with the following structural formula: (A) The invention further relates to the synthesis of intermediates useful in the preparation of Cariprazine.