| 861414-17-7

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二苯乙烯类
• CAS: 861414-17-7
• 化学式: C₁₇H₁₄N₂O₄
• 分子量: 310.309
• InChiKey: QYONXAWPVSTTBT-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 溶剂黄146 、 锌 作用下， 以 乙醇 为溶剂， 以84%的产率得到6,7-dimethoxy-3-phenylquinolin-2-amine
  参考文献：
  名称：

  Facile and Efficient Synthesis of 2-Aminoquinoline Derivatives Reduced by Zn/AcOH

  摘要：

  In this paper, a simple and efficient method for one-pot synthesis of 2-aminoquinolines was accomplished in good yields via reductive cyclization of nitro and cyano groups mediated by zinc/acetic acid is reported.

  DOI：

  10.3987/com-15-13368

文献信息

• Novel and efficient synthesis of substituted quinoline-1-oxides and the complex compounds SnL2Cl2 (L=2-aminoquinoline-1-oxides) with the aid of stannous chloride
  作者：Lei Fu、Wei Lin、Pan Xu、Yu-Kun Xi、Man-Man Wang、Da-Qing Shi

  DOI：10.1016/j.tet.2012.07.049

  日期：2012.9

  A novel and efficient approach to the synthesis of substituted quinoline-1-oxides and the complex compounds SnL2Cl2 (L=2-aminoquinoline-1-oxides) was developed. The reaction has fancy selectivity when 3-(2-nitrophenyl)acrylonitriles were treated with the aid of SnCl2 reagent under the same conditions. When R is -CN or -COOR' the complex compounds SnL2Cl2 (L=2-aminoquinoline-1-oxides) were obtained. Whereas, when R is H or aryl another series of substituted quinoline-1-oxides were formed. The products have been screened for their anticancer activities. (C) 2012 Elsevier Ltd. All rights reserved.