Cycloheptylsulfamate | 60900-58-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机硫酸及其衍生物
• 英文名称: Cycloheptylsulfamate
• 英文别名: cycloheptyl sulfamate
• CAS: 60900-58-5
• 化学式: C₇H₁₅NO₃S
• 分子量: 193.27
• InChiKey: NDIAXBSABFWAHX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS
  申请人：Salk Institute for Biological Studies

  公开号：EP3142699A1

  公开（公告）日：2017-03-22
• [EN] ORNITHINE- OR ASPARTATE-CONTAINING COMPOSITIONS AND THE USES THEREOF<br/>[FR] COMPOSITIONS COMPRENANT DE L'ORNITHINE OU DE L'ASPARTATE ET UTILISATIONS ASSOCIÉES
  申请人：WUHAN QR SCIENCE AND TECHNOLOGY DEV CO

  公开号：WO2014139469A1

  公开（公告）日：2014-09-18

  Methods and compositions comprising ornithine and/or aspartate that are useful for lowering one or more hyperlipidemic risk factor levels are described. More specifically, compositions comprising ornithine and/or aspartate that are useful for lowering lipid and/or lipoprotein levels, such as triglyceride, cholesterol and LDL levels, in the bloodstream in a subject are described. Methods of using compositions comprising ornithine and/or aspartate for ameliorating the side-effect induced by a therapeutic agent (e.g., statin) or a condition that is associated with an elevation of CPK (e.g., rhabdomyolysis or myopathy) are also described.
• [EN] COMPOSITIONS AND METHODS FOR TREATING METABOLIC DISORDERS<br/>[FR] COMPOSITIONS ET MÉTHODES POUR LE TRAITEMENT DE TROUBLES MÉTABOLIQUES
  申请人：SALK INST FOR BIOLOGICAL STUDI

  公开号：WO2015176017A1

  公开（公告）日：2015-11-19

  The disclosure features compositions and methods for treating a metabolic disorder associated with calcitonin gene-related peptide (CGRP), including diabetes, conditions associated with inhibition of insulin secretion, or for increasing longevity. Specifically, the methods comprise administering to a subject suffering a metabolic disorder a therapeutically effective amount of an anti-CGRP antagonist antibody.
• [EN] ORNITHINE-CONTAINING OR ASPARTATE-CONTAINING COMPOSITIONS AND THE USES THEREOF<br/>[FR] COMPOSITIONS CONTENANT DE L'ORNITHINE OU DE L'ASPARTATE ET LEURS UTILISATIONS
  申请人：WUHAN LL SCIENCE AND TECHNOLOGY DEV CO LTD

  公开号：WO2015161448A1

  公开（公告）日：2015-10-29

  Methods and compositions comprising ornithine and/or aspartate that are useful for lowering serum glucose level, treating diabetes or hyperglycemia are described. Methods of using compositions comprising ornithine and/or aspartate for ameliorating the side-effect induced by a therapeutic agent (e.g., anti-hyperglycemic agents) are also described.