4-(4-methoxycarbonyl-2-trifluoromethylphenyl)piperidine-1-carboxylic acid tert-butyl ester | 1204331-48-5
中文名称
——
中文别名
——
英文名称
4-(4-methoxycarbonyl-2-trifluoromethylphenyl)piperidine-1-carboxylic acid tert-butyl ester
英文别名
4-(4-methoxycarbonyl-2-trifluoromethyl-phenyl)-piperidine-1-carboxylic acid tert-butyl ester；tert-butyl 4-[4-methoxycarbonyl-2-(trifluoromethyl)phenyl]piperidine-1-carboxylate
CAS
1204331-48-5
化学式
C19H24F3NO4
mdl
——
分子量
387.399
InChiKey
ZLYVDQUCBXTMLC-UHFFFAOYSA-N
BEILSTEIN
——
EINECS
——
-
物化性质
-
计算性质
-
ADMET
-
安全信息
-
SDS
-
制备方法与用途
-
上下游信息
-
文献信息
-
表征谱图
-
同类化合物
-
相关功能分类
-
相关结构分类
物化性质
-
沸点：437.2±45.0 °C(Predicted)
-
密度：1.209±0.06 g/cm3(Predicted)
计算性质
-
辛醇/水分配系数(LogP)：4.1
-
重原子数：27
-
可旋转键数：5
-
环数：2.0
-
sp3杂化的碳原子比例：0.58
-
拓扑面积：55.8
-
氢给体数：0
-
氢受体数：7
上下游信息
-
上游原料
中文名称 英文名称 CAS号 化学式 分子量 —— 4-(4-methoxycarbonyl-2-trifluoromethylphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 1204331-26-9 C19H22F3NO4 385.383 -
下游产品
中文名称 英文名称 CAS号 化学式 分子量 —— 4-(4-carboxy-2-trifluoromethylphenyl)piperidine-1-carboxylic acid tert-butyl ester 1204331-27-0 C18H22F3NO4 373.372 —— 4-(4-methoxycarbonyl-2-trifluoromethyl-phenyl)piperidine-1-carboxylic acid benzyl ester 1204331-77-0 C22H22F3NO4 421.416 —— 4-(4-carboxy-2-trifluoromethyl-phenyl)-piperidine-1-carboxylic acid benzyl ester 1204331-78-1 C21H20F3NO4 407.389 —— 4-(1-acetylpiperidin-4-yl)-3-(trifluoromethyl)methylbenzoate 1204331-63-4 C16H18F3NO3 329.319 —— 4-piperidin-4-yl-3-trifluoromethyl-benzoic acid methyl ester 1204331-36-1 C14H16F3NO2 287.282 —— tert-butyl 4-[4-[(N'-phenylmethoxycarbonylcarbamimidoyl)carbamoyl]-2-(trifluoromethyl)phenyl]piperidine-1-carboxylate 1204331-50-9 C27H31F3N4O5 548.562 —— 4-(4-(N-tert-butoxycarbonyl)guanidinocarbonyl-2-trifluoromethyl-phenyl)piperidine-1-carboxylic acid benzyl ester 1204331-79-2 C27H31F3N4O5 548.562 —— 4-[1-(furan-2-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoic acid methyl ester 1204331-38-3 C19H18F3NO4 381.351 —— 4-[1-(furan-2-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoic acid 1204331-39-4 C18H16F3NO4 367.325 —— N-{4-[1-(2-methoxy-acetyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204329-30-5 C17H21F3N4O3 386.374 —— BI-9627 1204329-34-9 C16H19F3N4O2 356.348 —— N-[4-(1-propionyl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204329-28-1 C17H21F3N4O2 370.375 —— N-[4-(1-butyryl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204330-35-7 C18H23F3N4O2 384.401 —— 4-(4-guanidinocarbonyl-2-trifluoromethyl-phenyl)-piperidine-1-carboxylic acid amide 1204329-35-0 C15H18F3N5O2 357.335 —— N-[4-(1-isobutyryl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204329-29-2 C18H23F3N4O2 384.401 —— N-{4-[1-(2,2-dimethyl-propionyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204329-26-9 C19H25F3N4O2 398.428 —— N-{4-[1-(3-methyl-butyryl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204330-32-4 C19H25F3N4O2 398.428 —— N-[4-(1-cyclopropanecarbonyl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204329-24-7 C18H21F3N4O2 382.386 —— 1-(N-carbobenzyloxy)-3-[4-(1-cyclopropanecarbonyl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204331-61-2 C26H27F3N4O4 516.52 —— N-(4-piperidin-4-yl-3-trifluoromethylbenzoyl)-N'-(tert-butoxycarbonyl)guanidine 1204331-80-5 C19H25F3N4O3 414.428 —— benzyl N-[N-[4-(1-benzoylpiperidin-4-yl)-3-(trifluoromethyl)benzoyl]carbamimidoyl]carbamate 1204331-43-0 C29H27F3N4O4 552.553 —— N-[4-(1-cyclopentanecarbonyl-piperidin-4-yl)-3-trifluoromethyl-benzoyl]-guanidine 1204330-27-7 C20H25F3N4O2 410.439 —— N-(4-piperidin-4-yl-3-trifluoromethyl-benzoyl)-N'-(carbobenzyloxy)-guanidine 1204331-51-0 C22H23F3N4O3 448.445 —— N-{4-[1-(4-cyano-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-N'-(carbobenzyloxy)-guanidine 1204331-56-5 C30H26F3N5O4 577.563 —— N-{4-[1-(piperidine-3-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204329-53-2 C20H26F3N5O2 425.454 —— benzyl N-[amino-[[4-[1-(3-cyanobenzoyl)piperidin-4-yl]-3-(trifluoromethyl)benzoyl]amino]methylidene]carbamate 1393368-51-8 C30H26F3N5O4 577.563 —— N-{4-[1-(4-fluoro-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-N'-(carbobenzyloxy)-guanidine 1204331-53-2 C29H26F4N4O4 570.543 —— N-{4-[1-(4-chloro-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204330-29-9 C21H20ClF3N4O2 452.864 —— N-{4-[1-(4-fluoro-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204328-91-5 C21H20F4N4O2 436.409 —— N-{4-[1-(pyridine-4-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204329-41-8 C20H20F3N5O2 419.406 —— N-{4-[1-(3-chloro-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204330-30-2 C21H20ClF3N4O2 452.864 —— N-{4-[1-(biphenyl-4-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204330-86-8 C27H25F3N4O2 494.516 —— 1-(N-carbobenzyloxy)-3-{4-[1-(pyridine-3-carbonyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}guanidine 1204331-69-0 C28H26F3N5O4 553.541 —— N-{4-[1-(2-chloro-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-guanidine 1204330-33-5 C21H20ClF3N4O2 452.864 —— N-{4-[1-(4-methanesulfonyl-benzoyl)-piperidin-4-yl]-3-trifluoromethyl-benzoyl}-N'-(carbobenzyloxy)-guanidine 1204331-55-4 C30H29F3N4O6S 630.645