N,N'-Di-t-butyl-2,2-dimethyl-propan-1,3-diamin | 31892-17-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N'-Di-t-butyl-2,2-dimethyl-propan-1,3-diamin
• 英文别名: N,N'-ditert-butyl-2,2-dimethylpropane-1,3-diamine
• CAS: 31892-17-8
• 化学式: C₁₃H₃₀N₂
• 分子量: 214.395
• InChiKey: MIWVNHMIPANROR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  24.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• M3 muscarinic acetylcholine receptor antagonists
  申请人：Busch-Petersen Jakob

  公开号：US20070149598A1

  公开（公告）日：2007-06-28

  Novel thiazole aniline compounds, pharmaceutical compositions, methods of making them and uses thereof in treating M 3 muscarinic acetylcholine receptor mediated diseases are disclosed.
• Novel antibacterial agents
  申请人：Christensen G. Burton

  公开号：US20070196859A1

  公开（公告）日：2007-08-23

  This invention relates to novel multibinding compounds (agents) that are antibacterial agents. The multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands in their monovalent (i.e., unlinked ) state have the ability to bind to a an enzyme involved in cell wall biosynthesis and metabolism, a precursor used in the synthesis of the bacterial cell wall and/or the bacterial cell surface thereby interfere with the synthesis and/or metabolism of the cell wall. In particular the multibinding compounds of the invention comprise from 2-10 ligands covalently connected by a linker or linkers, wherein each of said ligands has a ligand domain capable of binding to penicillin binding proteins, a transpeptidase enzyme, a substrate of a transpeptidase enzyme, a beta-lactamase enzyme, penicillinase enzyme, cephalosporinase enzyme, a transglycosylase enzyme, or a transglycosylase enzyme substrate; Preferably, the ligands are selected from the beta lactam or glycopeptide class of antibacterial agents.
• 8-AZA Tetracycline Compounds
  申请人：Clark Roger B.

  公开号：US20120108569A1

  公开（公告）日：2012-05-03

  The present invention is directed to a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. The variables for Structural Formula I are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula I and its therapeutic use.
• US7384946B2
  申请人：——

  公开号：US7384946B2

  公开（公告）日：2008-06-10
• US8367654B2
  申请人：——

  公开号：US8367654B2

  公开（公告）日：2013-02-05