1,1'-{methylenebis[(1,4-phenylene)iminomethyl]}bis(2-naphthol) | 1236010-36-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 1,1'-{methylenebis[(1,4-phenylene)iminomethyl]}bis(2-naphthol)
• CAS: 1236010-36-8
• 化学式: C₃₅H₂₆N₂O₂
• 分子量: 506.604
• InChiKey: FECLBTRXQLVKAQ-BVDGQYGUSA-N

物化性质

• 熔点：
  248-250 °C
• 沸点：
  763.7±60.0 °C(Predicted)
• 密度：
  1.18±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  8.5
• 重原子数：
  39.0
• 可旋转键数：
  6.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.03
• 拓扑面积：
  65.18
• 氢给体数：
  2.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  4,4'-二氨基二苯甲烷 以65%的产率得到
  参考文献：
  名称：

  ABDOU N. A.; GHONEIM K. M.; KHALIFA M., EGYPT. J. PHARMAC. SCI., 1975, 16, NO 4, 469-475

  摘要：

  DOI：

文献信息

• Characterization of bis‐Schiff bases synthesized using ZnFe₂O₄nanoparticles as catalyst, and examination of their antibacterial and<i>in vitro</i>cytotoxic properties
  作者：Hamed Maaref、Enayatollah Sheikhhosseini、Mohammad Mehdi Foroughi、Mohammad Reza Akhgar、Shohreh Jahani

  DOI：10.1002/aoc.5557

  日期：2020.4

  In this study, ZnFe2O4 nanoparticles (NPs) were prepared by a hydro/solvothermal method, and their structures were characterized by infrared, scanning electron microscopy, energy‐dispersive X‐ray spectroscopy and X‐ray diffraction analyses. These ZnFe2O4 NPs were used in the synthesis of new bis‐Schiff bases by condensation of hydroxyl‐substituted aldehydes with various aromatic diamines in aqueous

  在这项研究中，采用水热/溶剂热法制备了ZnFe 2 O 4纳米颗粒（NPs），并通过红外，扫描电子显微镜，能量色散X射线光谱和X射线衍射分析对其结构进行了表征。这些ZnFe 2 O 4通过在水介质中将羟基取代的醛与各种芳族二胺缩合，NP用于合成新的双席夫碱。测试了合成的bis-Schiff碱基对革兰氏阴性和革兰氏阳性细菌的抗菌活性。MTT方法用于评估bis-Schiff碱基对人肺癌和乳腺癌细胞系的抗癌活性。结果表明这些化合物可被视为新的抗肿瘤候选药物。
• Design of postmetallocene catalytic systems of aryliminetype for olefins polymerization: XIII. Synthesis of tetradentate bis(2-hydroxy-1-naphthaldimine) ligands and their complexes with titanium(IV) dichloride
  作者：I. I. Oleinik、I. V. Oleinik、S. S. Ivanchev、G. A. Tolstikov

  DOI：10.1134/s1070428010050246

  日期：2010.5

  Reactions of 2-hydroxy-1-naphthaldehyde with 1,4-diaminobutane, 1,6-diaminohexane, 4,4'-methylenedianiline and its alkyl- and cycloalkyl-sybstituted derivatives, with 4,4'-sulfonyldianiline, 2,2'- and 4,4'-oxydianiline, 4,4'-(1,4-phenylenebisoxy)dianiline, 4,4'-[propane-2,2-diylbis(1,4-phenylenebisoxy)]dianiline, and p-terphenyl-4,4aEuro(3)-diamine afforded a series of the corresponding diimines that at treating with TiCl2(OPr-i)(2) formed mono- and binuclear complexes of titanium(IV) dichloride with tetradentate ligands LTiCl2 and L-2(TiCl2)(2).