N-[4-[[(2,6-二甲基-4-嘧啶基)氨基]磺基基]苯基]乙酰胺 | 825-48-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: N-[4-[[(2,6-二甲基-4-嘧啶基)氨基]磺基基]苯基]乙酰胺
• 英文名称: Ameisensaeure-(<3,4-dimethyl-pyridyl-(2)>-amid)
• 英文别名: N-(3,4-dimethyl-pyridin-2-yl)-formamide；N,N-dimethyl-N'-(pyridin-2-yl) formamide；N-(3,4-dimethylpyridin-2-yl)formamide
• CAS: 825-48-9
• 化学式: C₈H₁₀N₂O
• 分子量: 150.18
• InChiKey: JXGBVPVUWNUKGJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY
  申请人：Cannizzaro Carina

  公开号：US20090227543A1

  公开（公告）日：2009-09-10

  The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.

  本发明涉及磷酸酯取代化合物，具有免疫调节活性，含有这种化合物的组合物，以及包括这种化合物的给药的治疗方法，还涉及用于制备这种化合物的有用过程和中间体。
• IMMUNOMODULATOR PHOSPHONATE CONJUGATES
  申请人：GILEAD SCIENCES, INC.

  公开号：EP1620110A2

  公开（公告）日：2006-02-01
• IMIDAZO[4,5-B]PYRIDIN-2-ONE AND OXAZOLO[4,5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS THERAPEUTIC COMPOUNDS
  申请人：Cancer Research Technology Limited

  公开号：EP1812433B1

  公开（公告）日：2015-07-22
• [EN] PHOSPHONATE COMPOUNDS HAVING IMMUNO-MODULATORY ACTIVITY<br/>[FR] COMPOSES DE PHOSPHONATE PRESENTANT UNE ACTIVITE IMMUNOMODULATRICE
  申请人：GILEAD SCIENCES INC

  公开号：WO2004096236A2

  公开（公告）日：2004-11-11

  The invention is related to phosphonate substituted compounds having immuno-modulatory activity, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.