2-o-Hydroxyphenyl-6-nitro-4(3H)-chinazolinon | 28683-82-1

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 2-o-Hydroxyphenyl-6-nitro-4(3H)-chinazolinon
• 英文别名: 2-(2-hydroxy-phenyl)-6-nitro-3H-quinazolin-4-one；2-(2-hydroxyphenyl)-6-nitro-3H-quinazolin-4-one
• CAS: 28683-82-1
• 化学式: C₁₄H₉N₃O₄
• 分子量: 283.243
• InChiKey: IESSPWNZUHIYAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  21
• 可旋转键数：
  1
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  108
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• QUINAZOLINE-CONTAINING KITS FOR LABELING ALDEHYDE OR KETONE MOIETIES
  申请人：Haugland Richard P.

  公开号：US20110117659A1

  公开（公告）日：2011-05-19

  Novel fluorescent derivitization reagents are described that are suitable for coupling to biomolecules that contain aldehyde or ketone functional groups. In one embodiment is provided reagents that have the following formula: wherein Q is carbonyl, thiocarbonyl, or sulfonyl, and R 5 is -L-Z; L is arylene, or a C 1-6 perfluoroalkylene, or a single covalent bond; Z is a carbonyl hydrazide, hydrazide, sulfonyl hydrazide, or a thiocarbonyl hydrazide; R 11 -R 14 are independently H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 perfluoroalkyl, C 1-6 alkylamino, di(C 2-12 -alkyl)amino, amino, carboxy, cyano, halogen, hydroxy, nitro, phenyl, or sulfo; and R 21 -R 24 are independently H, C 1-6 alkyl, C 1-6 alkoxy, C 1-6 perfluoroalkyl, C 1-6 alkylamino, di(C 2-12 -alkyl)amino, amino, carboxy, cyano, halogen, hydroxy, nitro, phenyl, sulfo, or -L-Z. The method of treating a sample with the derivativization reagents is described. The reagents are particularly useful for labeling glycoproteins or glycopeptides, nucleic acids, and lipopolysaccharides in electrophoresis gels.
• US7816527B2
  申请人：——

  公开号：US7816527B2

  公开（公告）日：2010-10-19