(C6H5)3Sn((E)-3-(4-diphenylamino)phenyl)acrylate) | 1268244-70-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (C6H5)3Sn((E)-3-(4-diphenylamino)phenyl)acrylate)
• CAS: 1268244-70-7
• 化学式: C₃₉H₃₁NO₂Sn
• 分子量: 664.391
• InChiKey: QMSUZKMSZYDETO-AKZXYVTRSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  7.38
• 重原子数：
  43.0
• 可旋转键数：
  9.0
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  29.54
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  (E)-3-(4-(diphenylamino)phenyl)acrylic acid 、 三苯基氢氧化锡 以 苯 为溶剂， 以71%的产率得到(C6H5)3Sn((E)-3-(4-diphenylamino)phenyl)acrylate)
  参考文献：
  名称：

  Synthesis, crystal structures and in vitro antibacterial activity of two novel organotin(IV) complexes

  摘要：

  Two triorganotin(IV) carboxylates [nBu(3)SnOL](n) (KK1) and [Ph3SnOL](n) (KK2) have been prepared by the reactions of (E)-3-(4-(diphenylamino)phenyl)acrylic acid (HL) with n(Bu3Sn)(2)O and Ph3Sn(OH), respectively. Complexes KK1 and KK2 have been structurally characterized by IR, elemental analysis and X-ray crystallography, confirming that both complexes possess infinite 1D chain structures. It's exciting to discover that KK1 and KK2 exhibit strong solid-state luminescence emission while the HL almost quenches. Furthermore, both complexes were assayed for in vitro antibacterial activity against two Gram-positive bacterial strains (Bacillus subtilis ATCC 6633 and Staphylococcus aureus ATCC 6538) and two Gram-negative bacterial strains (Pseudomonas aeruginosa ATCC 13525 and Escherichia coli ATCC 35218) by MTT method. Complex KK2 exhibited powerful antibacterial activities against S. aureus with MIC value of 0.78 mu g/mL, which was superior to the positive controls penicillin G. On the basis of the biological results, structure-activity relationships were discussed. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2010.09.004