5-methyl-9-nitroindeno[2,1-e][1,3]thiazolo[3,2-a]pyrimidine-1,6(2H,10bH)-dione | 1225049-05-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 5-methyl-9-nitroindeno[2,1-e][1,3]thiazolo[3,2-a]pyrimidine-1,6(2H,10bH)-dione
• CAS: 1225049-05-7
• 化学式: C₁₄H₉N₃O₄S
• 分子量: 315.309
• InChiKey: RAKQGFUZDLRKHP-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  5-(3-nitrophenyl)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid ethyl ester 在 aluminum (III) chloride 、 乙酰氯 作用下， 以 硝基苯 为溶剂， 以60%的产率得到5-methyl-9-nitroindeno[2,1-e][1,3]thiazolo[3,2-a]pyrimidine-1,6(2H,10bH)-dione
  参考文献：
  名称：

  Synthesis Of Novel 5-Methylindeno[2,1E][1,3]Thiazolo[3,2-A]Pyrimidine-1,6(2H,10bH)-Diones

  摘要：

  Treatment of ethyl 5-aryl-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylic acid ethyl ester 1(a-h), with aluminum chloride and acetyl chloride in nitrobenzene gave the corresponding 5-Methylindeno[2,1-e][1,3]thiazolo[3,2-a]pyrimidine-1,6(2H,10bH)-dione derivatives 2(a-h). Yields of the products, after recrystallizing with acetic acid, were of the order of 46-67%. H-1-NMR and C-13-NMR spectroscopy, and elemental analysis were used for identification of these compounds.

  DOI：

  10.1515/hc.2009.15.5.351