Δ⁷-Tetrahydrocannabinol | 911802-23-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• 英文名称: Δ⁷-Tetrahydrocannabinol
• 英文别名: 6,6-dimethyl-9-methylene-3-pentyl-6a,7,8,9,10,10a-hexahydro-6H-benzo[c]chromen-1-ol；exo-THC；6,6-dimethyl-9-methylidene-3-pentyl-7,8,10,10a-tetrahydro-6aH-benzo[c]chromen-1-ol
• CAS: 911802-23-8
• 化学式: C₂₁H₃₀O₂
• 分子量: 314.468
• InChiKey: AOYYFUGUUIRBML-UHFFFAOYSA-N

物化性质

• 保留指数：
  2499.8

计算性质

• 辛醇/水分配系数(LogP)：
  7
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Δ⁷-Tetrahydrocannabinol 、 三氟化硼 、 乙醚 、 disodium;carbonate 、 重水 以95%的产率得到
  参考文献：
  名称：

  BANIJAMALI, ALI R.;ABOU-TALEB, NAGEH;VAN, DER SCHYF CORNELIS J.;CHARALAMB+, J. LABELL. COMPOUNDS AND RADIOPHARM., 25,(1988) N 1, 73-82

  摘要：

  DOI：

文献信息

• STABLE CANNABINOID COMPOSITIONS AND METHODS FOR MAKING AND STORING THEM
  申请人：Rossi Ronald

  公开号：US20120263785A1

  公开（公告）日：2012-10-18

  A composition comprising a high purity cannabinoid, an acid, and a pharmaceutically-acceptable solvent achieves room temperature stability for over 24 months. The acid improves the stability of the composition and the solvent enhances the solubility of the acid, thereby allowing the acid to have an improved stabilizing effect on the highly pure cannabinoid. Preferably, the solvent is an alcohol and, more preferably, the composition contains an oil. A method for making the composition includes combining the cannabinoid and the solvent and evaporating a portion of the solvent, along with adding an acid to the composition, before, during, or after the evaporating step. A method for making and storing the composition includes storing the composition in a manner adapted to maintain its stability. Pharmaceutical dosage forms include a formulated composition, such as having the oil. A method of treating a subject comprises administering to the subject the dosage form.
• US8980940B2
  申请人：——

  公开号：US8980940B2

  公开（公告）日：2015-03-17