1-苯基-1-氯四甲基二硅氧烷 | 36046-65-8

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 中文名称: 1-苯基-1-氯四甲基二硅氧烷
• 英文名称: 1-phenyl-1-chlorotetramethyldisiloxane
• 英文别名: 1.1.1.3-Tetramethyl-3-phenyl-3-chlor-disiloxan；Chloro-methyl-phenyl-trimethylsilyloxysilane
• CAS: 36046-65-8
• 化学式: C₁₀H₁₇ClOSi₂
• 分子量: 244.868
• InChiKey: IQHGZYWQELJWKV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.06
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-苯基-1-氯四甲基二硅氧烷 、 叔丁基过氧化氢 在 吡啶 作用下， 以 乙醚 为溶剂， 生成 tert-butylperoxy-methyl-phenyl-trimethylsilyloxysilane
  参考文献：
  名称：

  Brevnova, T. N.; Semenov, V. V.; Razuvaev, G. A., Journal of general chemistry of the USSR, 1981, vol. 51, p. 1729 - 1735

  摘要：

  DOI：
• 作为产物：
  描述：

  1-Chlor-1-phenyl-1,2,2,2-tetramethyldisilan 在 过氧化氢苯甲酰 作用下， 以 正己烷 为溶剂， 生成 1-苯基-1-氯四甲基二硅氧烷
  参考文献：
  名称：

  Semenov, V. V.; Brevnova, T. N.; Khorshev, S. Ya., Journal of general chemistry of the USSR, 1983, vol. 53, # 9, p. 1881 - 1887

  摘要：

  DOI：

文献信息

• Substituted lithiumtrimethylsiloxysilanides LiSiRR′(OSiMe3) – Investigations of their synthesis, stability and reactivity
  作者：Joerg Harloff、Eckhard Popowski、Helmut Reinke

  DOI：10.1016/j.jorganchem.2006.11.033

  日期：2007.3

  undergo partially self-condensation to afford the corresponding trimethylsiloxydisilanyllithiums Me3SiO(RR′Si)2Li (3a–g). (Me3)Si–O bond cleavage was observed for 2e and 2g–i. The relatively stable trimethylsiloxysilyllithiums 2f, 2g and 2i react with n-butyllithium under nucleophilic butylation to give the n-butyl-substituted silyllithiums nBuRR′SiLi (15g, 15f, 15i), which were trapped with Me3SiCl

  三甲基甲硅烷氧基氯硅烷（Me 3 SiO）RR'SiCl（1a – h：R'= Ph，1a：R = H，1b：R = Me，1c：R = Et，1d：R =  i Pr，1e： R =  t Bu，1f：R = Ph，1g：R = 2,4,6-Me 3 C 6 H 2（Mes），1h：R = 2,4,6-（Me 2 CH）3 C 6 H 2（小费）; 1i：R = R'= Mes），在-78°C的四氢呋喃（THF）中和在-110°C的THF /二乙醚/正戊烷的体积比为4：1：1的混合物中生成锂金属，生成：多种化合物的混合物。取决于取代基甲硅烷基锂衍生物（Me 3 SiO）RR'SiLi（2b - i），Me 3 SiO（RR'Si）2 Li（3a - g），Me 3 SiRR'SiLi（4a - h），（LiO） RR'SiLi（12e，12g – i），三硅氧烷（Me 3 SiO）2 SiRR'（5a
• Reactions of trimethylsiloxychlorosilanes with lithium metal – On the mechanism of the formation of trimethylsiloxysilyllithium compounds LiSiRR’(OSiMe3)
  作者：Joerg Harloff、Eckhard Popowski

  DOI：10.1016/j.jorganchem.2008.01.023

  日期：2008.4

  The reaction pathway for the formation of the trimethylsiloxysilyllithium compounds (Me3SiO)RR′SiLi (2a: R = Et, 2b: R = iPr, 2c: R = 2,4,6-Me3C6H2 (Mes); 2a–c: R′ = Ph; 2d: R = R′ = Mes) starting from the conversion of the corresponding trimethylsiloxychlorosilanes (Me3SiO)RR′SiCl (1a–d) in the presence of excess lithium in a mixture of THF/diethyl ether/n-pentane at −110 °C was investigated.

  形成三甲基甲硅烷氧基硅烷基锂化合物（Me 3 SiO）RR'SiLi（2a：R = Et，2b：R =  i Pr，2c：R = 2,4,6-Me 3 C 6 H 2（Mes ）；2a – c：R'= Ph；2d：R = R'= Mes），是在混合物中存在过量锂的情况下，由相应的三甲基甲硅烷氧基氯硅烷（Me 3 SiO）RR'SiCl（1a – d）转化而来在-110°C下研究了THF /二乙醚/正戊烷的合成。
• Razuvaev, G. A.; Brevnova, T. N.; Semenov, V. V., Journal of general chemistry of the USSR, 1987, vol. 57, p. 323 - 330
  作者：Razuvaev, G. A.、Brevnova, T. N.、Semenov, V. V.、Kornev, A. N.、Lopatin, M. A.、Egorochkin, A. N.

  DOI：——

  日期：——
• Reaktionen von Trimethylsiloxychlorsilanen (Me3SiO)Me2−nPhnSiCl (n=0,1,2) mit Lithium—Bildung von Trimethylsiloxy-substituierten Silyl- und Disilanyllithiumver- bindungen sowie Di- und Trisilanen
  作者：Jörg Harloff、Eckhard Popowski、Hans Fuhrmann

  DOI：10.1016/s0022-328x(99)00501-x

  日期：1999.12

  The trimethylsiloxychlorosilanes (Me3SiO)Me2-nPhnSiCl (1: n = 0; 2: n = 1; 3: n = 2) were allowed to react with lithium metal in tetrahydrofuran (THF) and in a mixture of THF-diethylether-n-pentane in volume ratio 4:1:1 (Trapp mixture). The reaction of 1 with lithium metal in TNF under refluxing leads to the home-coupling product [(Me3SiO)Me2Si](2) (4). A mixture of 1 and Me3SiCl in molar ratio 1:2 reacts with lithium metal in THF to give 4 and the cross-coupling product (Me3SiO)Me2SiSiMe3 (7). The silyllithium derivatives Me3SiO(SiMePh)(n)Li (8: n= 1; 9: n = 2; 10: n = 3) and Me3SiSiMePhLi (11) are formed in the reaction of 2 with lithium metal in THF at - 78 degrees C and in the Trapp mixture at - 110 degrees C. Main product in both cases is 9. 8-11 are trapped by Me3SiCl and HMe2SiCl. The trapping products (Me2SiO)SiMePhSiMe3 (13a), Me3SiO(SiMePh)(2)SiMe2R (14a, 14b; a: R = Me, b: R = H), Me3SiO(SiMePh)(3)SiMe2R (15a, 15b) and Me3SiSiMePhSiMe2R (16a, 16b) are obtained. The reaction of 3 with lithium metal like 2 produces the silyllithium derivatives Me3SiO(SiPh2)(n)Li (18: n = 1, 19: n = 2) and Me3SiSiPh2Li (20), wich are frapped by Me3SiCl and HMe2SiCl to give the corresponding disilanes (Me3SiO)SiPh2SiMe2R (23a, 23b) and trisilanes Me3SiO(SiPh)(2)SiMe2R (24a, 24b) as well as Me3SiSiPh2SiMe2R (25a, 25b). In addition to 18, 19 and 20 LiSiPh2SiPh2Li (21) is formed in a small amount in the reaction of 3 with lithium metal at - 78 degrees C to afford tetrasilanes [RMe2SiPh2Si](2) (26a, 26b) after trapping by Me3SiCl and HMe2SiCl. The disilane (Me3SiO)SiMeR'SiMe3 (17) (R' = 3,4,5,6-tetrakis(trimethylsilyl)cyclohex-1-enyl) is produced by reaction of a mixture of 2 and Me3SiCl in molar ratio 1:6 with 6 equivalents of lithium at - 78 degrees C in THF. The reaction of a mixture of 3 and Me3SiCl in the molar ratio 1:10 with 11 equivalents of lithium under the same conditions gives (Me3SiO)SiR'2SiMe3 (27).
• BREVNOVA, T. N.;SEMENOV, V. V.;RAZUVAEV, G. A., ZH. OBSHCH. XIMII, 1981, 51, N 9, 2010-2016
  作者：BREVNOVA, T. N.、SEMENOV, V. V.、RAZUVAEV, G. A.

  DOI：——

  日期：——