2-((E)-2-{2-Chloro-3-[2-[3-ethyl-3H-benzothiazol-(2E)-ylidene]-eth-(E)-ylidene]-cyclohex-1-enyl}-vinyl)-3-ethyl-benzothiazol-3-ium | 69415-20-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并噻唑类
• 英文名称: 2-((E)-2-{2-Chloro-3-[2-[3-ethyl-3H-benzothiazol-(2E)-ylidene]-eth-(E)-ylidene]-cyclohex-1-enyl}-vinyl)-3-ethyl-benzothiazol-3-ium
• 英文别名: (2Z)-2-[(2Z)-2-[2-chloro-3-[(E)-2-(3-ethyl-1,3-benzothiazol-3-ium-2-yl)ethenyl]cyclohex-2-en-1-ylidene]ethylidene]-3-ethyl-1,3-benzothiazole
• CAS: 69415-20-9
• 化学式: C₂₈H₂₈ClN₂S₂
• 分子量: 492.129
• InChiKey: SNGJGLALPFHEPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  60.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-羟基苯硫酚 、 2-((E)-2-{2-Chloro-3-[2-[3-ethyl-3H-benzothiazol-(2E)-ylidene]-eth-(E)-ylidene]-cyclohex-1-enyl}-vinyl)-3-ethyl-benzothiazol-3-ium 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 以61 %的产率得到(E)-3-ethyl-2-(2-(6-hydroxy-2,3-dihydro-1H-thioxanthen-4-yl)vinyl)benzo[d]thiazol-3-ium
  参考文献：
  名称：

  一种新型溶酶体靶向近红外荧光探针，用于特异性检测半胱氨酸、同型半胱氨酸和谷胱甘肽

  摘要：

  本文通过修饰噻吨-苯并噻唑鎓荧光团BCy-Cys，合成了一种溶酶体靶向近红外（NIR）荧光探针，用于检测同型半胱氨酸（Hcy）/谷胱甘肽（GSH）中的半胱氨酸（Cys）。正如预期的那样，与 Hcy/GSH 相比，BCy-Cys 对 Cys 的检测表现出高选择性和高灵敏度，检测限极低，为 0.31 μM，并具有明显的颜色变化。HRMS 证实，795 nm 处的荧光强度因分子内电荷转移 (ICT) 的增强而显着增强。重要的是，BCy-Cys 可用于可视化外源性和内源性溶酶体 Cys，这表明其在复杂生物系统中的潜在应用。

  DOI：

  10.3390/molecules28176189

文献信息

• ETHYLENICALLY UNSATURATED COMPOUND, LIGHT SENSITIVE COMPOSITION, LIGHT SENSITIVE PLANOGRAPHIC PRINTING PLATE MATERIAL AND PRINTING PROCESS EMPLOYING THE SAME
  申请人：Kuroki Takaaki

  公开号：US20090263744A1

  公开（公告）日：2009-10-22

  The present invention provides a novel ethylenically unsaturated compound which is highly sensitive to scanning exposure due to an ultraviolet to near-infrared laser and is cured to give good physical properties; a light sensitive composition providing good developability and high sensitivity and forming a high strength layer; a planographic printing plate material having advantages that good developability, high sensitivity and high strength layer are obtained, particularly a planographic printing plate material requiring no developing machine which are mounted on a printing press without any development, followed by printing and which provides excellent developability on a printing press and printing durability; and a printing process. The ethylenically unsaturated compound has in the molecule a photo-oxidation group and a polymerizable ethylenically unsaturated bond, and has a predetermined solubility in water or an aqueous alkali solution. The planographic printing plate material is characterized in that it comprises a support and provided thereon, a light sensitive layer containing the ethylenically unsaturated compound, a polyhalogen compound as a photopolymerization initiator, a water-soluble polymer binder as a polymer binder and an infrared absorbing agent.
• INFRARED FLUORESCENT COMPOSITION HAVING POLYVINYL ACETAL BINDER
  申请人：Widzinski Thomas J.

  公开号：US20130087740A1

  公开（公告）日：2013-04-11

  A composition is disclosed that includes a dye that fluoresces in the infrared region of the electromagnetic spectrum and a polyvinyl acetal binder. The weight ratio of the dye relative to the combined weight of the dye and binder is in a range of 0.001 to 0.025.
• INK HAVING POLYVINYL ACETAL BINDER
  申请人：Widzinski Thomas J.

  公开号：US20130087741A1

  公开（公告）日：2013-04-11

  An ink is disclosed that includes a solvent, a dye that fluoresces in the infrared region of the electromagnetic spectrum and a polyvinyl acetal binder. The weight ratio of the dye relative to the combined weight of the dye and binder is in a range of 0.001 to 0.025.
• ARTICLE PRINTED WITH INFRARED DYE
  申请人：Widzinski Thomas J.

  公开号：US20130089713A1

  公开（公告）日：2013-04-11

  A printed article is disclosed including a substrate and printed data that is not visible to the unaided eye. The printed data includes a dye that fluoresces in the infrared region of the electromagnetic spectrum and a polyvinyl acetal binder. The weight ratio of the dye relative to the combined weight of the dye and binder is in a range of 0.001 to 0.025.
• US7220530B2
  申请人：——

  公开号：US7220530B2

  公开（公告）日：2007-05-22