[Zn(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol)(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol-H)]ClO4 | 1432047-21-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: [Zn(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol)(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol-H)]ClO4
• 英文别名: [Zn(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol)(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol-H)]ClO₄
• CAS: 1432047-21-6
• 化学式: C₁₃H₁₄N₃O*C₁₃H₁₅N₃O*ClO₄*Zn
• 分子量: 622.396
• InChiKey: KJBMIZXFSMDVES-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -1.19
• 重原子数：
  40.0
• 可旋转键数：
  10.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.23
• 拓扑面积：
  195.89
• 氢给体数：
  1.0
• 氢受体数：
  12.0

反应信息

• 作为产物：
  描述：

  zinc perchlorate 、 2-(((3-(1H-imidazol-1-yl)propyl)imino)methyl)phenol 以 甲醇 为溶剂， 反应 2.0h， 以65%的产率得到[Zn(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol)(2-([3-(1H-imidazol-1-yl)propyl]aminopropyliminomethyl)phenol-H)]ClO4
  参考文献：
  名称：

  Imidazole Schiff base ligands: Synthesis, coordination complexes and biological activities

  摘要：

  1-(3-Aminopropyl)imidazole (Apim) reacts with salicylaldehyde and a selection of imidazole aldehydes and the resulting Schiff base ligands readily coordinate to Zn(II), Cu(II) and Ag(I) centres. X-ray crystal structures were obtained for two of the free ligands and also the Ag(I) complex of the Apim-salicylaldehyde ligand. Encouragingly, all of free ligands and most of their metal complexes are relatively non-toxic, in vivo, towards Galleria mellonella. Although the free ligands and the Cu(II) and Zn(II) complexes are inactive, in vitro, against a selection of microbial pathogens, most of the Ag(I) complexes exhibit moderate anti-bacterial activity and good anti-fungal activity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2013.03.023