N,N-Dimethyl-N'-<2-hydroxy-ethyl>-p-phenylendiamin | 91800-22-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N,N-Dimethyl-N'-<2-hydroxy-ethyl>-p-phenylendiamin
• 英文别名: 2-(4-dimethylamino-anilino)-ethanol；2-(4-Dimethylamino-anilino)-aethanol；N.N-Dimethyl-N'-(β-oxy-aethyl)-p-phenylendiamin；2-[4-(Dimethylamino)anilino]ethanol
• CAS: 91800-22-5
• 化学式: C₁₀H₁₆N₂O
• 分子量: 180.25
• InChiKey: DUMYZASYTUXZPC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  35.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N,N-Dimethyl-N'-<2-hydroxy-ethyl>-p-phenylendiamin 在 三乙胺 、 三氯氧磷 作用下， 生成 <(2-Chlor-ethyl)-(4-dimethylamino-phenyl)-amino>-sulfinsaeure-ethylester
  参考文献：
  名称：

  Yaguzhinskii,L.S.; Berlin,A.Y., Journal of general chemistry of the USSR, 1964, vol. 34, p. 2146 - 2149

  摘要：

  DOI：
• 作为产物：
  描述：

  环氧乙烷 、 N,N-二甲基-对苯二胺 生成 N,N-Dimethyl-N'-<2-hydroxy-ethyl>-p-phenylendiamin
  参考文献：
  名称：

  Yaguzhinskii,L.S.; Berlin,A.Y., Journal of general chemistry of the USSR, 1964, vol. 34, p. 2146 - 2149

  摘要：

  DOI：

文献信息

• Jacobs; Heidelberger, Journal of Biological Chemistry, 1915, vol. 21, p. 445
  作者：Jacobs、Heidelberger

  DOI：——

  日期：——
• Sulphonamide Derivatives
  申请人：Heino Jyrki

  公开号：US20090023735A1

  公开（公告）日：2009-01-22

  The invention relates to sulphonamide derivatives of formula (I), where R C is selected from a group consisting of dialkylamino, NO 2 , CN, aminocarbonyl, monoalkylaminocarbonyl, dialkylaminocarbonyl, alkanoyl, oxazol-2-yl, oxazolylaminocarbonyl, aryl, aroyl, aryl-CH(OH)—, arylaminocarbonyl, furanyl, where the aryl, aroyl and furanyl moieties may be substituted, guanidinyl-(CH 2 ) z —N(R′)—, Het-(CH 2 ) z —N(R′)—, Het-CO—N(R′)—, Het-CH(OH)— and Het-CO—, where Het is an optionally substituted 4-6-membered heterocyclic ring containing one or more heteroatoms sleeted from N, S and O, R′ is hydrogen or alkyl, and z is an integer 1 to 5; R A is a group of formula (A), (B), (C) or (D) as defined in the claims; and R B is hydrogen, alkyl, alkanoyl, hydroxyalkyl, alkoxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, aminoalkyl, mono- or dialkylaminoalkyl or Het-alkyl, where Het is as defined above. The invention also relates to the use of derivatives of formula (I) as inhibitors for collagen receptor integrins and a process for preparing sulphonamides of formula (II).
• Yaguzhinskii,L.S.; Berlin,A.Y., Journal of general chemistry of the USSR, 1964, vol. 34, p. 2146 - 2149
  作者：Yaguzhinskii,L.S.、Berlin,A.Y.

  DOI：——

  日期：——