4-(2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butane-1-sulfonyl chloride | 859875-16-4

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• 英文名称: 4-(2-propyl-1H-imidazo[4,5-c][1,5]naphthyridin-1-yl)butane-1-sulfonyl chloride
• 英文别名: 4-(2-Propylimidazo[4,5-c][1,5]naphthyridin-1-yl)butane-1-sulfonyl chloride
• CAS: 859875-16-4
• 化学式: C₁₆H₁₉ClN₄O₂S
• 分子量: 366.871
• InChiKey: BWWIHHICLWSJEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  24
• 可旋转键数：
  7
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  86.1
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES
  申请人：3M Innovative Properties Company

  公开号：EP1699788A2

  公开（公告）日：2006-09-13
• IMIDAZOQUINOLINYL SULFONAMIDES
  申请人：Bonk Jason D.

  公开号：US20090062272A1

  公开（公告）日：2009-03-05

  Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamide compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.
• US8735421B2
  申请人：——

  公开号：US8735421B2

  公开（公告）日：2014-05-27
• [EN] IMIDAZOQUINOLINYL, IMIDAZOPYRIDINYL, AND IMIDAZONAPHTHYRIDINYL SULFONAMIDES<br/>[FR] SULFONAMIDES D'IMIDAZOQUINOLINYLE, D'IMIDAZOPYRIDINYLE ET D'IMIDAZONAPHTYRIDINYLE
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2005066169A2

  公开（公告）日：2005-07-21

  Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamide compounds, pharmaceutical compositions containing the compounds, intermediates, and methods of making and methods of use of these compounds as immunomodulators, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases are disclosed.