N-Aethyl-1.5-dimethyl-hexylamin | 91014-01-6

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: N-Aethyl-1.5-dimethyl-hexylamin
• 英文别名: 2-Ethylamino-6-methylheptan；N-ethyl-6-methylheptan-2-amine
• CAS: 91014-01-6
• 化学式: C₁₀H₂₃N
• mdl: MFCD11161065
• 分子量: 157.299
• InChiKey: LESHAHLRHJPYKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Compositions and Methods for Inducing Cell Dedifferentiation
  申请人：Chen Shuibing

  公开号：US20070254884A1

  公开（公告）日：2007-11-01

  The present invention provides compositions and methods for dedifferentiating lineage committed mammalian cells.

  本发明提供了用于去分化已分化系谱哺乳动物细胞的组合物和方法。
• COMPOSITIONS AND METHODS FOR INDUCING CELL DEDIFFERENTIATION
  申请人：Chen Shuibing

  公开号：US20100022533A1

  公开（公告）日：2010-01-28

  The present invention provides compounds, compositions and methods for dedifferentiating lineage committed mammalian cells into stem cells. The present invention also provides methods of inducing dedifferentiation of lineage committed mammalian cells into stem cells, which can be further differentiated into various lineage committed cells. Methods of identifying additional compounds useful for inducing dedifferentiation of lineage committed cells into stem cells are also provided.

  本发明提供了将已分化的系谱承诺哺乳动物细胞转化为干细胞的化合物、组合物和方法。本发明还提供了诱导已分化的系谱承诺哺乳动物细胞转化为干细胞的方法，这些干细胞可以进一步分化为各种系谱承诺的细胞。本发明还提供了用于诱导已分化的系谱承诺细胞转化为干细胞的其他有用化合物的鉴定方法。
• NITROGENATED HETEROCYCLIC RING DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME
  申请人：Idemitsu Kosan Co., Ltd.

  公开号：EP2524913B1

  公开（公告）日：2017-07-26
• Biarylurea derivatives
  申请人：Hayama Takashi

  公开号：US20070027147A1

  公开（公告）日：2007-02-01

  The present invention relates to a compound of Formula (I) and the manufacturing method(s) thereof and the use thereof: Formula (I) wherein: Ar is a nitrogen-containing heteroaromatic ring group; X and Z are each a carbon atom, and so on; Y is CO, and so on; R 1 is a hydrogen atom, and so on; R 2 and R 3 are each a hydrogen atom, and so on; R 4 and R 5 are each a hydrogen atom, and so on; and the formula is a single bond or a double bond. According to the present invention, the compound of the present invention can provide Cdk4 and/or Cdk6 inhibitors for treating malignant tumors, because the compounds of the present invention exhibit a prominent growth inhibitory activity against tumor cells.
• USP14 Inhibitors for Treating or Preventing Viral Infections
  申请人：PRESIDENT AND FELLOWS OF HARVARD COLLEGE

  公开号：US20150335652A1

  公开（公告）日：2015-11-26

  Disclosed herein are methods of treating or preventing a viral infection resulting from infection by a flavivirus, comprising administering to a subject a small molecule inhibitor of USP14, represented by Formula (I) or a pharmaceutically acceptable salt, solvate, hydrate, prodrug, chemically-protected form, enantiomer or stereoisomer thereof, and pharmaceutical compositions comprising an effective amount of a compound of Formula (I) for use in the method.