| 1268310-53-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1268310-53-7
• 化学式: C₁₉H₁₃Cl₂N₅O₃S
• 分子量: 462.316
• InChiKey: PAABUXNBUNPFIG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.07
• 重原子数：
  30.0
• 可旋转键数：
  5.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  117.1
• 氢给体数：
  3.0
• 氢受体数：
  7.0

反应信息

• 作为反应物：
  描述：

  、 3-{4-[4-amino-2-nitrobenzyl]-3-nitrophenyl}-7-chloro-2-phenylquinazolin-4(3H)-one 在 盐酸 、 sodium nitrite 、 sodium carbonate 作用下， 以 水 为溶剂， 反应 4.0h， 以80%的产率得到7-chloro-3-(4-(4-((2-((4-chloro-6-((4-chlorophenyl)amino)-1,3,5-triazin-2-yl)amino)naphthalen-1-yl)diazenyl)-2-nitrobenzyl)-3-nitrophenyl)-2-phenylquinazolin-4(3H)-one
  参考文献：
  名称：

  Synthesis, antimicrobial activity and application of some novel quinazolinone based monoazo reactive dyes on various fibres

  摘要：

  The main target of this paper was to synthesize novel reactive dyes that not only give good dyeing property but also show pharmacological activity i.e. antimicrobial activity (antibacterial and antifungal). In this regard ten novel monoazo quinazolinone based reactive dyes (7a-j) were made by coupling of diazotised 3-{4-[4-amino-2-nitrobenzyl]-3-nitrophenyl}-7-chloro-2-phenylquinazolin-4(3H)-one (4) with various p-chloro anilino cyanurated coupling components (6a-j). The structures of all these synthesized dyes were confirmed by elemental analysis and spectral methods. The antimicrobial activity, colorimetric data, solvent effect and fastness properties of these dyes were also investigated. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.dyepig.2010.10.013