3-Dimethylamino-1.2-bis-propyldisulfido-propan | 688-67-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 3-Dimethylamino-1.2-bis-propyldisulfido-propan
• 英文别名: N,N-dimethyl-2,3-bis(propyldisulfanyl)propan-1-amine
• CAS: 688-67-5
• 化学式: C₁₁H₂₅NS₄
• 分子量: 299.59
• InChiKey: BSQDTCSBJMZETR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  16
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  104
• 氢给体数：
  0
• 氢受体数：
  5

文献信息

• LIPID CONTAINING FORMULATIONS
  申请人：MANOHARAN Muthiah

  公开号：US20120046478A1

  公开（公告）日：2012-02-23

  Compositions and methods useful in administering nucleic acid based therapies, for example association complexes such as liposomes and lipoplexes are described.

  本文描述了在进行核酸基础治疗时有用的组合物和方法，例如关联复合物，如脂质体和脂质复合物。
• 2'-F MODIFIED RNA INTERFERENCE AGENTS
  申请人：Manoharan Muthiah

  公开号：US20110269814A1

  公开（公告）日：2011-11-03

  This invention relates to a method of modulating the expression of a target gene in an organism comprising administering an iRNA agent, wherein the iRNA comprises at least one 2′-deoxy-2′-fluoro (2′-F) nucleotide in the antisense strand and at least one modified nucleotide in the sense strand. The invention also relates to compositions comprising a single-stranded oligonucleotide that contains at least one 2′-deoxy-2′-fluoro (2′-F) nucleotide. siRNA molecule containing these oligonucleotides have decreased immunogenicity.
• US8034376B2
  申请人：——

  公开号：US8034376B2

  公开（公告）日：2011-10-11
• US8642076B2
  申请人：——

  公开号：US8642076B2

  公开（公告）日：2014-02-04