N-butyl-4-(N-methy-2-bromoethyl amino)-1,8-naphthalimide | 1430411-66-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 异喹啉及其衍生物
• 英文名称: N-butyl-4-(N-methy-2-bromoethyl amino)-1,8-naphthalimide
• CAS: 1430411-66-7
• 化学式: C₁₉H₂₁BrN₂O₂
• 分子量: 389.292
• InChiKey: VSHUVHOGSQBDMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.07
• 重原子数：
  24.0
• 可旋转键数：
  6.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  40.62
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  N-丁基苯胺 、 N-butyl-4-(N-methy-2-bromoethyl amino)-1,8-naphthalimide 在 三乙胺 作用下， 以 乙二醇甲醚 为溶剂， 以57%的产率得到2-butyl-6-[2-(N-butylanilino)ethyl-methylamino]benzo[de]isoquinoline-1,3-dione
  参考文献：
  名称：

  Rational design of fluorescent viscosity sensors by the principle of photoinduced electron transfer

  摘要：

  To establish a new strategy for the development of fluorescent viscosity sensors by the principle of photoinduced electron transfer, three 4-aminonaphthalimide based D-(CH2)(2)-A molecules were designed and synthesized. The effects of solvent polarity and viscosity on the fluorescence spectra of these compounds were investigated. These compounds exhibit viscosity-sensitive fluorescence spectra in ethylene glycol-glycerol mixtures. A mechanism about exciplex formation was proposed to explain their viscosity sensitivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.02.111
• 作为产物：
  描述：

  4-bromo-N-butylnaphthalimide 在 三溴化磷 、 三乙胺 作用下， 以 二氯甲烷 、 乙二醇甲醚 为溶剂， 反应 5.0h， 生成 N-butyl-4-(N-methy-2-bromoethyl amino)-1,8-naphthalimide
  参考文献：
  名称：

  Rational design of fluorescent viscosity sensors by the principle of photoinduced electron transfer

  摘要：

  To establish a new strategy for the development of fluorescent viscosity sensors by the principle of photoinduced electron transfer, three 4-aminonaphthalimide based D-(CH2)(2)-A molecules were designed and synthesized. The effects of solvent polarity and viscosity on the fluorescence spectra of these compounds were investigated. These compounds exhibit viscosity-sensitive fluorescence spectra in ethylene glycol-glycerol mixtures. A mechanism about exciplex formation was proposed to explain their viscosity sensitivity. (C) 2013 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2013.02.111