| 1234864-67-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并吡喃
• CAS: 1234864-67-5
• 化学式: C₆₃H₆₅N₉O₄
• 分子量: 1012.27
• InChiKey: JESQUFIYXIDJDR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  12.24
• 重原子数：
  76.0
• 可旋转键数：
  16.0
• 环数：
  11.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  109.65
• 氢给体数：
  0.0
• 氢受体数：
  11.0

反应信息

• 作为产物：
  描述：

  吡啶-2,6-二甲醛 、 若丹明B酰肼 以 乙醇 为溶剂， 反应 12.0h， 以85.4%的产率得到
  参考文献：
  名称：

  Single- and Multiphoton Turn-On Fluorescent Fe³⁺ Sensors Based on Bis(rhodamine)

  摘要：

  Selective and sensitive turn-on fluorescent Fe3+ sensors based on novel bis(rhodamine) dye molecules are reported. The compounds are synthesized with very high yields and characterized with NMR, ESI mass spectrometry, and elemental analysis. Single- and two-photon fluorescence enhancement is observed for both molecules in the presence of Fe3+. High selectivity and sensitivity is observed over other metal ions and is shown to be due mainly to the spirolactam ring-opening power of Fe3+. All measurements are made in buffer environments simulating biological conditions to facilitate single- and multiphoton fluorescence imaging or Fe3+ in vivo and in vitro. Larger enhancement of fluorescence for both one- and two-photon excitation makes them suitable candidates for fluorescent labeling of biological systems. Two photon cross-section and time-resolved fluorescence measurements are utilized to understand the selectivity of the present sensors for Fe3+-sensing.

  DOI：

  10.1021/jp1034568