3α,20βF-Diacetoxy-5β-pregnan-17-ol | 115303-64-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 类固醇和类固醇衍生物
• 英文名称: 3α,20βF-Diacetoxy-5β-pregnan-17-ol
• 英文别名: 3α,20β(F)-Diacetoxy-5β-pregnan-17α-ol；(10S)-17t-hydroxy-3t-acetoxy-10r.13c-dimethyl-17c-((R)-1-acetoxy-ethyl)-(5cH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthrene；(10S)-17t-Hydroxy-3t-acetoxy-10r.13c-dimethyl-17c-((R)-1-acetoxy-aethyl)-(5cH.8cH.9tH.14tH)-hexadecahydro-1H-cyclopenta[a]phenanthren；[(3R,5R,8R,9S,10S,13S,14S,17R)-17-[(1R)-1-acetyloxyethyl]-17-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl] acetate
• CAS: 115303-64-5
• 化学式: C₂₅H₄₀O₅
• 分子量: 420.59
• InChiKey: COXXOOWTEWCQRW-FXQIGAMPSA-N

物化性质

• 沸点：
  491.2±10.0 °C(predicted)
• 密度：
  1.13±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.64
• 重原子数：
  30.0
• 可旋转键数：
  3.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  72.83
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  (17Z)-5β-pregn-17(20)-en-3α-ol 在 吡啶 、 四氧化锇 、 乙醚 作用下， 生成 3α,20βF-Diacetoxy-5β-pregnan-17-ol
  参考文献：
  名称：

  Preschoolers' Inhibition in Their Home: Relation to Temperament

  摘要：

  Researchers assessed 58 preschoolers' reactions to an unfamiliar person and unfamiliar objects in their familiar home environment. Children participated in a 30-min procedure designed to elicit behavioral inhibition, including (a) a free-play period with a stranger present, (b) a structured interaction with the stranger, and (c) uncertainty-eliciting tasks, Behaviors representing the child's reactions toward the mother, stranger, and novel objects were coded, Mothers completed a temperament scale. Preschoolers exhibited behaviors indicative of inhibition toward unfamiliar social and nonsocial stimuli; behaviors remained stable across increasingly intrusive episodes. The approach/withdrawal component of temperament was related to behavioral inhibition. Individual differences in mood did not appear to be related to differences in inhibition. Parent reported temperament was related to researcher-observed behaviors.

  DOI：

  10.1080/00221320209598688