2,3-dihydroxy-N-(5-phenyl-[1,3,4]thiadiazol-2-yl)-succinamic acid | 1241907-46-9

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2,3-dihydroxy-N-(5-phenyl-[1,3,4]thiadiazol-2-yl)-succinamic acid
• CAS: 1241907-46-9
• 化学式: C₁₂H₁₁N₃O₅S
• 分子量: 309.302
• InChiKey: SIUVHZLPECBVPM-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  在 甲醇 、 potassium carbonate 作用下， 反应 12.0h， 以5.31 g的产率得到2,3-dihydroxy-N-(5-phenyl-[1,3,4]thiadiazol-2-yl)-succinamic acid
  参考文献：
  名称：

  Synthesis of Novel Succinic Acid Derivatives as Potential Matrix Metalloproteinases Inhibitors and Anticancer Medicine

  摘要：

  In this paper we have designed different methods, according to the differences in nucleophilicity of amino, to conjugate tartaric acid or malic acid with two kinds of useful intermediates respectively via amide bond, envisaging they are promising matrix metalloproteinase inhibitors or anticancer medicine.

  DOI：

  10.2174/157017810790796336