4-Methyl-2-(N,N-dimethylamino)-symm.-triazin | 22404-37-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 4-Methyl-2-(N,N-dimethylamino)-symm.-triazin
• 英文别名: dimethyl-(4-methyl-[1,3,5]triazin-2-yl)-amine；N,N,4-trimethyl-1,3,5-triazin-2-amine
• CAS: 22404-37-1
• 化学式: C₆H₁₀N₄
• 分子量: 138.172
• InChiKey: HHKPKUHIZXTEKR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• [EN] MITOCHONDRIAL MODULATION TO IMPROVE METABOLIC SYNDROME DURING AGING<br/>[FR] MODULATION MITOCHONDRIALE POUR AMÉLIORER LE SYNDROME MÉTABOLIQUE PENDANT LE VIEILLISSEMENT
  申请人：UNIV LELAND STANFORD JUNIOR

  公开号：WO2021034548A1

  公开（公告）日：2021-02-25

  Compounds, compositions and methods are provided for mitochondrial modulation. The subject mitochondrial modulator compounds generally include a head group linked to a charged moiety. In certain cases, the head group is a heterocyclic or a heteroaryl group. Aspects of the subject methods include a method of modulating mitochondria. Aspects of the subject methods include treating a subject having a metabolic syndrome-related disease or a symptom thereof by administering to the subject a therapeutically effective amount of a subject compound. In certain cases, the disease is selected from hyperlipidemia, type 2 diabetes, fatty liver disease, obesity, cardiovascular disease and stroke. In certain cases, the symptom is selected from abdominal obesity, insulin resistance, hyperinsulinemia, high levels of blood fats, increased blood pressure, and elevated serum lipids.

  提供了用于线粒体调节的化合物、组合物和方法。所述线粒体调节剂化合物通常包括与带电基团相连的头基团。在某些情况下，头基团是杂环或杂芳基团。所述方法的方面包括调节线粒体的方法。所述方法的方面包括通过向患有代谢综合征相关疾病或其症状的患者施用所述化合物的治疗有效量来治疗患者。在某些情况下，该疾病选自高脂血症、2型糖尿病、脂肪肝病、肥胖症、心血管疾病和中风。在某些情况下，该症状选自腹部肥胖、胰岛素抵抗、高胰岛素血症、高血脂水平、高血压和血清脂质升高。
• COMPOUNDS AND MARKERS FOR SURFACE-ENHANCED RAMAN SCATTERING
  申请人：Küstner Bernd

  公开号：US20100284917A1

  公开（公告）日：2010-11-11

  The present invention relates to compounds and markers for surface-enhanced Raman scattering (SERS), and methods for the preparation of the SERS markers. The present invention further relates to compositions, methods and uses, wherein the present SERS markers are employed.

  本发明涉及用于表面增强拉曼散射（SERS）的化合物和标记物，以及制备SERS标记物的方法。本发明还涉及使用本SERS标记物的组合物、方法和用途。
• NOVEL BENZYLAMINE DERIVATIVES AND THEIR UTILITY AS CHOLESTEROL ESTER-TRANSFER PROTEIN INHIBITORS
  申请人：DR. REDDY'S LABORATORIES LTD.

  公开号：US20140134235A1

  公开（公告）日：2014-05-15

  The present invention provides, among other things, new benzylamine compounds, compositions comprising benzylamine compounds, methods of making benzylamine compounds, and methods of using benzylamine compounds for treating or preventing a variety of conditions or diseases associated with lipoprotein metabolism.

  本发明提供了新的苄基胺化合物，包括苄基胺化合物的组合物，制备苄基胺化合物的方法，以及使用苄基胺化合物治疗或预防与脂蛋白代谢有关的各种疾病或症状的方法。
• Adhesive resin compositions, laminates, production method thereof and oriented films
  申请人：Mitsubishi Chemical Corporation

  公开号：EP0857758A1

  公开（公告）日：1998-08-12

  According to the present invention, there is provided an adhesive resin composition comprising 50 - 99% by weight of a modified hydrogenated block copolymer (a), which is obtained by hydrogenating a block copolymer of a vinyl aromatic compound and a conjugated diene compound followed by modification with an unsaturated carboxylic acid or a derivative thereof, wherein the content of the unsaturated carboxylic acid or the derivative thereof is 0.01 - 20% by weight, and 1 - 50% by weight of a tackifier (b), and a laminate and an oriented film wherein such adhesive resin composition is used for the adhesive layer. The adhesive resin composition of the present invention is useful in various fields such as film packaging of foods and pharmaceutical preparations.

  根据本发明，提供了一种粘合剂树脂组合物，该组合物包含 50 - 99% （重量）的改性氢化嵌段共聚物 (a)，该嵌段共聚物是通过氢化乙烯基芳香族化合物和共轭二烯化合物的嵌段共聚物，然后用不饱和羧酸或其衍生物进行改性而得到的，其中不饱和羧酸或其衍生物的含量为 0.01-20%(重量)，增粘剂(b)的含量为 1-50%(重量)。本发明的粘合剂树脂组合物可用于各种领域，如食品和药物制剂的薄膜包装。
• Compounds and markers for surface-enhanced raman scattering
  申请人：Julius-Maximilians-Universität Würzburg

  公开号：EP2040075A1

  公开（公告）日：2009-03-25

  The present invention relates to compounds and markers for surface-enhanced Raman scattering (SERS), and methods for the preparation of the SERS markers. The present invention further relates to compositions, methods and uses, wherein the present SERS markers are employed.

  本发明涉及用于表面增强拉曼散射（SERS）的化合物和标记物，以及制备 SERS 标记物的方法。本发明还涉及使用本发明 SERS 标记的组合物、方法和用途。