6-O-乙酰基抗坏血酸 | 20229-76-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氢呋喃
• 中文名称: 6-O-乙酰基抗坏血酸
• 英文名称: 6-O-Acetylascorbic acid
• 英文别名: [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] acetate
• CAS: 20229-76-9
• 化学式: C₈H₁₀O₇
• 分子量: 218.16
• InChiKey: JOGHFNRWGSNDFS-MHTLYPKNSA-N

物化性质

• 熔点：
  148-149 °C(Solv: benzene (71-43-2); acetone (67-64-1))
• 沸点：
  340.2±42.0 °C(Predicted)
• 密度：
  1.689±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.1
• 重原子数：
  15
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  113
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为产物：
  描述：

  维生素 C 、 乙酸乙烯酯 以 叔丁醇 为溶剂， 反应 20.0h， 以to yield 4.8 g of a crude ascorbic acid-6-acetate的产率得到6-O-乙酰基抗坏血酸
  参考文献：
  名称：

  Process for the stereoselective esterification of ascorbic or erythorbic

  摘要：

  在有活性脂肪酶的存在下，将抗坏血酸或山梨酸与有机酸烯醇酯在有机溶剂中反应，其中抗坏血酸或山梨酸在25°C时的溶解度超过0.3％，从而产生抗坏血酸或山梨酸的有机酸酯。

  公开号：

  US05455174A1

文献信息

• PHOSPHINE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEROXIDE SCAVENGER USING THE SAME
  申请人：Shioji Kosei

  公开号：US20110015440A1

  公开（公告）日：2011-01-20

  The invention provides a novel peroxide scavenger comprising a phosphine compound represented by general formula [I]: wherein Z 1 and Z 2 each represents a cyclic group; Ar represents an arylene group; R represents an aliphatic hydrocarbon group; Y represents phosphorus (P), nitrogen (N), or bismuth (Bi); and R 1 , R 2 , and R 3 each represents a cyclic group, particularly a peroxide scavenger that can scavenge peroxides such as reactive oxygen species which are generated in mitochondria upon exposure to oxidative stress and localized in mitochondria. The phosphine compound of the invention is oxidized by the peroxides localized in mitochondria to increase the fluorescence intensity, whereby the peroxides can be scavenged.

  该发明提供了一种新型过氧化物清除剂，包括由通式[I]所表示的膦化合物：其中Z1和Z2分别表示环状基团；Ar表示芳基基团；R表示脂肪烃基团；Y表示磷（P）、氮（N）或铋（Bi）；而R1、R2和R3分别表示环状基团，特别是一种过氧化物清除剂，可以清除在暴露于氧化应激时在线粒体中生成并定位在线粒体中的反应性氧化物种，该发明的膦化合物被定位在线粒体中的过氧化物氧化以增加荧光强度，从而可以清除过氧化物。
• ASCORBIC ACID-RELATED COMPOUND AND PLANT ANTIVIRAL AGENT
  申请人：NIPPON SODA CO., LTD.

  公开号：US20150250169A1

  公开（公告）日：2015-09-10

  The present invention provides a compound represented by formula (1) (wherein each of X 1 and X 2 independently represents —OR 1 , —NR 2 R 3 or —CR 4 R 5 R 6 or the like, each of R 1 , R 2 , R 3 , R 4 , R 5 and R 6 independently represents an unsubstituted or substituent-bearing glycosyl group or an unsubstituted or substituent-bearing C1 to C30 alkyl group or the like, and A represents an unsubstituted or substituent-bearing C1 to C30 alkyl group or the like) or a salt thereof.

  本发明提供一种由式（1）表示的化合物（其中X1和X2分别独立表示—OR1，—NR2R3或—CR4R5R6或类似物，R1、R2、R3、R4、R5和R6分别独立表示未取代或取代基的糖基或未取代或取代基的C1到C30烷基或类似物，A表示未取代或取代基的C1到C30烷基或类似物）或其盐。
• Process for producing organic acid esters
  申请人：MITSUBISHI RAYON CO., LTD

  公开号：EP0514694A1

  公开（公告）日：1992-11-25

  An organic acid ester of ascorbic acid or erythorbic acid is produced by reacting ascorbic acid or erythorbic acid with an organic acid enol ester in an organic solvent with a solubility of ascorbic acid or erythorbic acid of more than 0.3% at 25°C in the presence of an active lipase.

  抗坏血酸或赤藓红酸的有机酸酯是在 25°C 时，在有活性脂肪酶存在的情况下，将抗坏血酸或赤藓红酸与有机酸烯醇酯在溶解度大于 0.3% 的有机溶剂中反应制得的。
• Process for producing ascorbic or erythorbic acid esters
  申请人：MITSUBISHI RAYON CO., LTD

  公开号：EP0514694B1

  公开（公告）日：1997-07-23
• SINGLE-COMPONENT ADHESIVE COMPOSITIONS
  申请人：Ohio State Innovation Foundation

  公开号：US20220135842A1

  公开（公告）日：2022-05-05

  Disclosed are single component, stimuli-responsive adhesives that cure in response to an applied stimulus, including single component moisture-curable adhesives (e.g., moisture-curable (meth)acrylate/polyurethane hybrid adhesives). These adhesive compositions can combine the non-toxic, high strength properties of (meth)acrylate adhesives with the bonding characteristics of polyurethanes. The compositions described herein employ imitator systems which trigger polymerization/curing of the adhesive composition in response to a stimulus, such as ambient moisture, mild heat, and/or by physical stress. These strategies eliminate the need for mixing or an external energy stimulus to initiate curing. In this way, the benefits of polyurethane adhesive chemistry can be brought to the consumer market, in a system that is readily usable by the average individual.