(1R,4S,4aR,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one | 1224700-87-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: (1R,4S,4aR,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one
• CAS: 1224700-87-1
• 化学式: C₂₅H₄₁NO₃Si
• 分子量: 431.691
• InChiKey: YLWBOHMDKNSEFG-ILJKJKDTSA-N

反应信息

• 作为产物：
  描述：

  在 sodium tetrahydroborate 、 二苯基二硒醚 作用下， 以 乙醇 为溶剂， 反应 0.5h， 生成 (1R,4R,4aS,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one 、 (1R,4S,4aS,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one 、 (1R,4R,4aR,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one 、 (1R,4S,4aR,8aS)-4a-hydroxy-8a-methyl-4-[(methyl(phenyl)amino)methyl]-1-[(tert-butyldimethylsilyl)oxy]-octahydronaphthalen-6(7H)-one
  参考文献：
  名称：

  First total synthesis of (+)-Carainterol A

  摘要：

  The first, stereospecific, and elegant synthesis of the natural product (+)-Carainterol A was developed by using the Robinson annulation reaction as a key step to build the eudesmane skeleton. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2010.02.001