4-(hydroxymethyl)piperidine-1-carbodithioic acid | 1287753-19-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 哌啶类
• 英文名称: 4-(hydroxymethyl)piperidine-1-carbodithioic acid
• 英文别名: 4-(Hydroxymethyl)piperidine-1-carbodithioic acid
• CAS: 1287753-19-8
• 化学式: C₇H₁₃NOS₂
• 分子量: 191.318
• InChiKey: VDMJQOINXRMZIR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  56.6
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(hydroxymethyl)piperidine-1-carbodithioic acid 以 乙醇 、 水 、 丙酮 为溶剂， 反应 10.0h， 生成
  参考文献：
  名称：

  Synthesis, spectroscopy, and biological activity of heterobimetallic complexes containing Sn(IV) and Pd(II) with 4-(hydroxymethyl)piperidine-1-carbodithioic acid

  摘要：

  4-(Hydroxymethyl)piperidine-1-carbodithioic acid has been synthesized by reacting 4-piperidinemethanol with carbon disulfide at room temperature. The synthesized ligand was treated with organotin(IV) chlorides to yield organotin complexes. These complexes by further treatment with palladium chloride afford heterobimetallic complexes containing Sn(IV) and Pd(II). The synthesized complexes along with ligand has been characterized by elemental analysis, FTIR, NMR (H-1, C-13) spectroscopy. The IR data confirmed the complexation through the sulfur and oxygen donor sites of the ligand. NMR data revealed the tetrahedral geometry in the solution. Biological activity was checked against selected bacterial and fungal strains. All complexes along with the ligand were found to be biologically active with few exceptions.

  DOI：

  10.1134/s1070363213120311
• 作为产物：
  描述：

  4-哌啶甲醇 、 二硫化碳 以 乙醇 为溶剂， 反应 3.0h， 生成 4-(hydroxymethyl)piperidine-1-carbodithioic acid
  参考文献：
  名称：

  Synthesis, spectroscopy, and biological activity of heterobimetallic complexes containing Sn(IV) and Pd(II) with 4-(hydroxymethyl)piperidine-1-carbodithioic acid

  摘要：

  4-(Hydroxymethyl)piperidine-1-carbodithioic acid has been synthesized by reacting 4-piperidinemethanol with carbon disulfide at room temperature. The synthesized ligand was treated with organotin(IV) chlorides to yield organotin complexes. These complexes by further treatment with palladium chloride afford heterobimetallic complexes containing Sn(IV) and Pd(II). The synthesized complexes along with ligand has been characterized by elemental analysis, FTIR, NMR (H-1, C-13) spectroscopy. The IR data confirmed the complexation through the sulfur and oxygen donor sites of the ligand. NMR data revealed the tetrahedral geometry in the solution. Biological activity was checked against selected bacterial and fungal strains. All complexes along with the ligand were found to be biologically active with few exceptions.

  DOI：

  10.1134/s1070363213120311

文献信息

• Synthesis, spectroscopy, and biological activity of heterobimetallic complexes containing Sn(IV) and Pd(II) with 4-(hydroxymethyl)piperidine-1-carbodithioic acid
  作者：M. T. Anwar、S. Ali、S. Shahzadi、M. Shahid

  DOI：10.1134/s1070363213120311

  日期：2013.12

  4-(Hydroxymethyl)piperidine-1-carbodithioic acid has been synthesized by reacting 4-piperidinemethanol with carbon disulfide at room temperature. The synthesized ligand was treated with organotin(IV) chlorides to yield organotin complexes. These complexes by further treatment with palladium chloride afford heterobimetallic complexes containing Sn(IV) and Pd(II). The synthesized complexes along with ligand has been characterized by elemental analysis, FTIR, NMR (H-1, C-13) spectroscopy. The IR data confirmed the complexation through the sulfur and oxygen donor sites of the ligand. NMR data revealed the tetrahedral geometry in the solution. Biological activity was checked against selected bacterial and fungal strains. All complexes along with the ligand were found to be biologically active with few exceptions.