5-(N,N-diethylamino)pentanethiol | 101153-37-1

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 5-(N,N-diethylamino)pentanethiol
• 英文别名: 5-(Diethylamino)pentane-1-thiol
• CAS: 101153-37-1
• 化学式: C₉H₂₁NS
• 分子量: 175.338
• InChiKey: XXQRFWNVDYUFKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  4.2
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• [EN] NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF<br/>[FR] NOUVEAUX DÉRIVÉS DE CYCLOSPORINE ET LEURS UTILISATIONS
  申请人：S&T GLOBAL INC

  公开号：WO2017200984A1

  公开（公告）日：2017-11-23

  A compound of the Formula (I) is disclosed: (I) or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification. Also described are a pharmaceutical composition comprising the same and a method for treating or preventing viral infections, inflammation, dry eye, central nervous disorders, cardiovascular diseases, cancer, obesity, diabetes, muscular dystrophy, lung, and liver, and kindey diseases, and hair loss using the same.

  公开了化合物的公式（I）：（I）或其药学上可接受的盐，其中符号如规范中定义。还描述了包含相同化合物的药物组合物，以及使用该药物组合物治疗或预防病毒感染、炎症、干眼症、中枢神经障碍、心血管疾病、癌症、肥胖症、糖尿病、肌肉萎缩症、肺部和肝脏疾病、肾脏疾病和脱发的方法。
• Omega-quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal antiinflammatory drugs
  申请人：SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED

  公开号：EP0289262A2

  公开（公告）日：1988-11-02

  Quaternary ammonium alkyl esters and thioesters of acidic nonsteroidal anti-inflammatory drugs (NSAIDs) are disclosed. These esters and thioesters display the anti-­inflammatory profile of the parent NSAIDs with greatly reduced gastrointestinal irritancy, providing a more favorable separation of therapeutic activity and toxicological side effects than the parent NSAIDs.

  本发明公开了酸性非甾体抗炎药（NSAIDs）的季铵烷基酯和硫代酯。这些酯类和硫代酯类具有母体非甾体抗炎药的抗炎特性，但胃肠道刺激性大大降低，与母体非甾体抗炎药相比，能更有效地将治疗活性和毒副作用分开。
• Liquid two-component coating compositions
  申请人：E. I. du Pont de Nemours and Company

  公开号：EP2514778A1

  公开（公告）日：2012-10-24

  The invention relates to two-component liquid coating composition comprising: A) at least one compound with functional groups reactive towards reactive functional groups of cross-linking agent B), B) at least one cross-linking agent with reactive functional groups and C) at least one catalyst compound having at least one urethane and/or at least one urea group and at least one tertiary amine group, said catalyst compound is present as particles having a melting temperature of 40 to 180°C.

  本发明涉及双组分液体涂料组合物，包括 A) 至少一种化合物，其官能团对交联剂 B) 的活性官能团具有反应性、 B) 至少一种具有活性官能团的交联剂，以及 C) 至少一种具有至少一个氨基甲酸酯和/或至少一个脲基和至少一个叔胺基团的催化剂化合物，所述催化剂化合物以颗粒形式存在，熔化温度为 40 至 180°C。
• Modified ion exchange resins and use thereof
  申请人：MITSUBISHI CHEMICAL CORPORATION

  公开号：EP0676237B1

  公开（公告）日：1999-03-17
• Liquid Two-Component Coating Compositions
  申请人：Flosbach Carmen

  公开号：US20110237742A1

  公开（公告）日：2011-09-29

  The invention relates to two-component liquid coating composition comprising: A) at least one compound with functional groups reactive towards reactive functional groups of cross-linking agent B), B) at least one cross-linking agent with reactive functional groups and C) at least one catalyst compound having at least one urethane and/or at least one urea group and at least one tertiary amine group, said catalyst compound is present as particles having a melting temperature of 40 to 180° C.