4-嘧啶羧酸,2-氯-6-(三氟甲基)- | 84489-09-8

• 分子结构分类: 有机化合物 - 有机氮化合物
• 中文名称: 4-嘧啶羧酸,2-氯-6-(三氟甲基)-
• 中文别名: 亚胺磷酰胺
• 英文名称: Iminocyclophosphamide
• 英文别名: N,N-bis(2-chloroethyl)-2-oxo-5,6-dihydro-1,3,2λ5-oxazaphosphinin-2-amine
• CAS: 84489-09-8
• 化学式: C₇H₁₃Cl₂N₂O₂P
• 分子量: 259.07
• InChiKey: WCPGXZCOHAERPQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.3
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  41.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• Biocatalytic solgel microarrays
  申请人：Dordick S. Jonathan

  公开号：US20070059779A1

  公开（公告）日：2007-03-15

  A system and method for conducting high-throughput interactions between test compositions and analytes, comprising one or more test compositions, and a plurality of independent micromatrices, wherein each said micromatrix encapsulates at least one said test composition; and said micromatrices are made of a material that is permeable to an analyte.
• METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES USING IMMUNOMODULATORY AGENTS
  申请人：Kaplin Adam Ian

  公开号：US20120237472A1

  公开（公告）日：2012-09-20

  The present invention provides compositions and methods for treating and/or preventing an autoimmune disease comprising administering to a subject in need thereof an effective amount of cyclophosphamide and/or a cyclophosphamide derivative in combination with an additional immunomodulatory agent.
• US7846747B2
  申请人：——

  公开号：US7846747B2

  公开（公告）日：2010-12-07
• [EN] METHODS AND COMPOSITIONS FOR TREATING OR PREVENTING AUTOIMMUNE DISEASES USING IMMUNOMODULATORY AGENTS<br/>[FR] MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT OU LA PRÉVENTION DE MALADIES AUTO-IMMUNES UTILISANT DES AGENTS IMMUNOMODULATEURS
  申请人：UNIV JOHNS HOPKINS

  公开号：WO2011011706A2

  公开（公告）日：2011-01-27

  The present invention provides compositions and methods for treating and/or preventing an autoimmune disease comprising administering to a subject in need thereof an effective amount of cyclophosphamide and/or a cyclophosphamide derivative in combination with an additional immunomodulatory agent.