4-(2-thiazolylazo)resorcinol | 101515-17-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 4-(2-thiazolylazo)resorcinol
• 英文别名: 4-n-dodecyl-6-(2-thiazolylazo)-resorcinol
• CAS: 101515-17-7
• 化学式: C₂₁H₃₁N₃O₂S
• 分子量: 389.562
• InChiKey: UUTQTYWSLQQPPO-WCWDXBQESA-N

物化性质

• 沸点：
  547.5±58.0 °C(Predicted)
• 密度：
  1.15±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  7.43
• 重原子数：
  27.0
• 可旋转键数：
  13.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  78.07
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为产物：
  描述：

  2-氨基噻唑 、 4-十二烷基间苯二酚 生成 4-(2-thiazolylazo)resorcinol
  参考文献：
  名称：

  通过 4-n-十二烷基-6-(2-噻唑基拉唑)间苯二酚从强碱性介质中提取钴 (II)、镍 (II) 和铜 (II)

  摘要：

  合成了一种新的提取试剂4-n-dodecyl-6-(2-thiazolylazo)resorcinol。该试剂的萃取特性已针对几种重金属离子进行了检测。钴 (II)、镍 (II) 和铜 (II) 可以从强碱性溶液中提取为 4-甲基-2-戊酮，而无需额外的有机试剂，如季铵盐。

  DOI：

  10.1246/cl.1986.225

文献信息

• Naked-Eye Cadmium Sensor:  Using Chromoionophore Arrays of Langmuir−Blodgett Molecular Assemblies
  作者：Deivasigamani Prabhakaran、Ma Yuehong、Hiroshi Nanjo、Hideyuki Matsunaga

  DOI：10.1021/ac0623540

  日期：2007.6.1

  This study demonstrates the possibility of a reversible naked-eye detection method for submicromolar levels of cadmium(II) using the Langmuir-Blodgett (L-B) technique. Molecular assemblies of 4-n-dodecyl-6-(2-thiazolylazo)resorcinol are transferred on precleaned microscopic glass slides, to act as a sensing probe. Isotherm (pi-A) measurements were performed to ensure the films' structural rigidity

  这项研究证明了使用Langmuir-Blodgett（LB）技术对亚微摩尔水平的镉（II）进行可逆的裸眼检测方法的可能性。将4-正十二烷基-6-（2-噻唑基偶氮）间苯二酚的分子组装体转移到预先清洁的显微镜载玻片上，以用作传感探针。进行等温线（pi-A）测量以确保传感器制造过程中薄膜的结构刚度和均匀性。使用原子力显微镜和扫描电子显微镜对传感器的表面形态进行表征。探针膜呈现出可见的颜色过渡，在很宽的浓度范围（0.04-44.5 microM）上与镉形成一系列的红橙色到粉红色紫色的复合物。镉响应动力学和传感器的变化 使用吸收光谱法监测固有的光学性质，并使用X射线光电子能谱法进一步证实。为了提高传感器的性能，研究了聚乙烯基硬脂酸酯和聚乙烯基N-十八烷基氨基甲酸酯的混合LB薄膜复合材料。测试了该传感器的实用方法，以证明使用合成混合物和真实水样在常见基质成分中对镉的选择性和灵敏度。使用传感器条，镉的检测和定量的下限分别为0
• METHOD OF STABILIZING PEPTIDE CONTAINED IN BIOSAMPLE
  申请人：KYOWA MEDEX CO., LTD.

  公开号：EP1921453A1

  公开（公告）日：2008-05-14

  The present invention provides a simple method for the stabilization of a peptide in a biological sample and a reagent for the stabilization, a simple method for the preservation of a biological sample comprising a peptide and a reagent for the preservation, and a method for the accurate measurement of a peptide in a biological sample and a reagent for the measurement. Addition of a saccharide to a biological sample enables the stabilization of a peptide in the biological sample, the preservation of the biological sample comprising a peptide in a stable condition and the accurate measurement of a peptide in the biological sample. As the present invention can stabilize a peptide in a biological sample collected in the clinical examination, the peptide as a marker in the biological sample can be measured accurately in the clinical examination.

  本发明提供了一种稳定生物样品中肽的简单方法和稳定试剂，一种保存包含肽的生物样品的简单方法和保存试剂，以及一种精确测量生物样品中肽的方法和测量试剂。在生物样品中加入糖类可以稳定生物样品中的多肽，将包含多肽的生物样品保存在稳定的状态下，并精确测量生物样品中的多肽。由于本发明可以稳定临床检查中采集的生物样本中的多肽，因此可以在临床检查中准确测量生物样本中作为标记物的多肽。
• METHOD FOR STABILIZATION OF PEPTIDES IN A BIOLOGICAL SAMPLE
  申请人：Aoyama Norihito

  公开号：US20090035803A1

  公开（公告）日：2009-02-05

  The present invention provides a simple method for the stabilization of a peptide in a biological sample and a reagent for the stabilization, a simple method for the preservation of a biological sample comprising a peptide and a reagent for the preservation, and a method for the accurate measurement of a peptide in a biological sample and a reagent for the measurement. Addition of a saccharide to a biological sample enables the stabilization of a peptide in the biological sample, the preservation of the biological sample comprising a peptide in a stable condition and the accurate measurement of a peptide in the biological sample. As the present invention can stabilize a peptide in a biological sample collected in the clinical examination, the peptide as a marker in the biological sample can be measured accurately in the clinical examination.
• Metal ion sensor and fabricating method thereof
  申请人：Char Kookheon

  公开号：US20100252807A1

  公开（公告）日：2010-10-07

  A metal ion sensor is provided. The metal ion sensor includes a nanoparticle core doped with a first luminescent material and a shell enclosing the nanoparticle core. The shell includes a second luminescent material and binding sites of outer metal ions. The first luminescent material and the second luminescent material emit light with mutually different colors when excited by an excitation source. The luminescence intensity of the light emitted from the second luminescent material varies in accordance with the binding amount of the outer metal ions, such that the emission color of the combined luminescence of the first luminescent material and the second luminescent material is changed.
• US8173385B2
  申请人：——

  公开号：US8173385B2

  公开（公告）日：2012-05-08