N,N'-ethylene-bis-(2-hydroxy-α-methylbenzylamine) | 91915-31-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: N,N'-ethylene-bis-(2-hydroxy-α-methylbenzylamine)
• 英文别名: 2,2′-{ethane-1,2-diylbis[nitrile(1E)eth-1-yl-1-ylidene]}diphenol；2-(1-(2-(1-(2-hydroxyphenyl)ethylamino)ethylamino)ethyl)phenol；2,2'-((Ethane-1,2-diylbis(azanediyl))bis(ethane-1,1-diyl))diphenol；2-[1-[2-[1-(2-hydroxyphenyl)ethylamino]ethylamino]ethyl]phenol
• CAS: 91915-31-0
• 化学式: C₁₈H₂₄N₂O₂
• 分子量: 300.401
• InChiKey: CTTJKTVUMBSNHI-UHFFFAOYSA-N

物化性质

• 沸点：
  465.8±35.0 °C(Predicted)
• 密度：
  1.133±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  64.5
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  nickel(II) chloride hexahydrate 、 N,N'-ethylene-bis-(2-hydroxy-α-methylbenzylamine) 以 乙醇 、 水 为溶剂， 以58%的产率得到
  参考文献：
  名称：

  Synthesis, Characterisation and Electrochemical Behaviour of some Nickel(II) Complexes with Linear and Tripodal Tetradentate Ligands Derived From Schiff Bases

  摘要：

  A number of new six-coordinate Ni(II) complexes with linear and tripodal tetradentate ligands having the general formula [Ni(H2L)(H2O)(2)]Cl-2 . xH(2)O have been synthesized. Microanalysis, molar conductance, IR spectra, thermogravimetric analysis, magnetic measurements, and electronic spectra have been used to elucidate their structure. The experimental data show that the ligands are bonded in a non-deprotonated form and are coordinated in a tetradentate manner, the other axial sites being occupied by the aquo molecules. On the basis of electronic results it is concluded that tripodal ligands exert the strongest ligand field and the ligand substituents affect the ligand field strength which increases with the electron donating effect of the R group. The electrochemical behaviour of the nickel(II) complexes was determined by cyclic voltammetry which shows that chelate structure, ligand geometry and electron donating effect of the ligand substituents are among the factors influencing the redox potentials of the complexes. Also, we note that the ligands used in the present study can stabilize both the nickel(I) and the nickel(III) states.

  DOI：

  10.1080/00945719708000259
• 作为产物：
  描述：

  2'-羟基苯乙酮 在 甲醇 、 sodium tetrahydroborate 、 potassium hydroxide 作用下， 以 乙醇 、 二氯甲烷 为溶剂， 反应 2.0h， 生成 N,N'-ethylene-bis-(2-hydroxy-α-methylbenzylamine)
  参考文献：
  名称：

  一些还原的席夫碱衍生物的合成和抗菌研究

  摘要：

  在NaBH 4存在下，通过席夫碱中间体，由2-羟基苯甲醛衍生物和1,2-二胺衍生物反应制得了一系列N，N-取代的乙烯-1,2-二胺衍生物。筛选合成的化合物的抗菌活性。化合物SB01，SB02和SB09在MIC为0.40-6.25μg/ mL时显示出显着的活性。

  DOI：

  10.13005/ojc/340616

文献信息

• Exploration of selective recognition of iodide with dipodal sensor: 2,2′-[ethane-1,2-diylbis(iminoethane-1,1-diyl)]diphenol
  作者：Kundan Tayade、Judith Gallucci、Hemant Sharma、Sanjay Attarde、Rahul Patil、Narinder Singh、Anil Kuwar

  DOI：10.1039/c3dt52690a

  日期：——

  A dipodal fluorescent receptor, 2,2′-[ethane-1,2-diylbis(iminoethane-1,1-diyl)]diphenol (2), with amine and hydroxyl moieties as binding sites has been synthesised and characterized with spectroscopic methods and single crystal X-ray techniques. The recognition of the anions with receptor 2 was studied using UV-Vis and fluorescence spectroscopy. The 1H-NMR spectroscopic and DFT studies revealed the distinct recognition of I− ions over the other surveyed anions.

  合成了一种双足荧光受体 2,2α-[乙烷-1,2-二基双(亚氨基乙烷-1,1-二基)]联苯酚 (2)，以胺和羟基部分作为结合位点，并用光谱方法进行了表征和单晶X射线技术。使用紫外-可见光和荧光光谱研究了受体 2 对阴离子的识别。 1H-NMR 光谱和 DFT 研究揭示了 I−离子相对于其他调查阴离子的独特识别。
• Synthesis, characterization and electrochemical behaviour of cobalt(II) and cobalt(III):O2− complexes, respectively, with linear and tripodal tetradentate ligands derived from Schiff bases
  作者：S Djebbar-Sid、O Benali-Baitich、J.P Deloume

  DOI：10.1016/s0022-2860(00)00968-6

  日期：2001.7

  the redox potentials of the complexes. Linear ligands lead to high-spin cobalt(II) complexes. They do not interact with dioxygen and stabilize the Co(II) state counter to their related Schiff-base complexes. The low-spin complexes with tripodal ligands are O 2 adducts and the configuration in these complexes is best formulated as [Co III O 2 − ].

  摘要 使用元素分析、摩尔电导、红外光谱、磁测量、电子和 ESR 光谱合成并表征了具有源自席夫碱的线性和三足四齿配体的新型八面体钴配合物。实验结果支持具有两个 N 和两个 O 供体位点的线性配体与钴离子的结合。它们显示出方形平面几何形状和仅通过一个氮原子与金属离子配位的三足配体，给出了 NO 3 供体基团的排列，其他轴向位点被分子氧和/或水分子占据。循环伏安法的结果表明，螯合结构和配体几何结构以及配体取代基的给电子效应是影响配合物氧化还原电位的因素之一。线性配体导致高自旋钴 (II) 配合物。它们不与分子氧相互作用并稳定 Co(II) 状态，使其与其相关的席夫碱配合物相反。具有三足配体的低自旋配合物是 O 2 加合物，这些配合物中的构型最好表述为 [Co III O 2 - ]。
• Patel, Kalpana V.; Bhattacharya, Pabitra K., Indian Journal of Chemistry, Section A: Inorganic, Physical, Theoretical and Analytical, 1984, vol. 23, # 6, p. 527 - 529
  作者：Patel, Kalpana V.、Bhattacharya, Pabitra K.

  DOI：——

  日期：——