8-Methyl-isoxanthopterin | 3149-35-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 蝶啶及其衍生物
• 英文名称: 8-Methyl-isoxanthopterin
• 英文别名: 8-Methyl isoxanthopterin；2-amino-8-methyl-3H-pteridine-4,7-dione
• CAS: 3149-35-7
• 化学式: C₇H₇N₅O₂
• 分子量: 193.165
• InChiKey: SLNSAAHOIROZOZ-UHFFFAOYSA-N

物化性质

• 沸点：
  352.4±52.0 °C(Predicted)
• 密度：
  1.86±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.9
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  100
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  8-Methyl-isoxanthopterin 、 丙醇 在 ammonium peroxydisulfate 、 phosphate buffer 作用下， 以54%的产率得到6-(1-hydroxypropyl)-8-methylisoxanthoperin
  参考文献：
  名称：

  Synthesis of asperopterin-B and some analogues

  摘要：

  DOI：

  10.1016/s0040-4039(00)84942-4

文献信息

• HYDROGELS FOR THE CONTROLLED RELEASE OF BIOACTIVE MATERIALS
  申请人：LEHN Jean-Marie

  公开号：US20080057005A1

  公开（公告）日：2008-03-06

  The present invention relates to the formation of hydrogels based on guanosine hydrazide derivatives in the presence of cations. The hydrogels can be used as a carrier/delivery system for biologically active substances such as flavors, fragrances, insect attractants or repellents, bactericides, fungicides, pharmaceuticals or agrochemicals.

  本发明涉及在阳离子存在下基于鸟苷肼衍生物形成水凝胶。该水凝胶可以用作生物活性物质（如香料、香味、昆虫引诱剂或驱虫剂、杀菌剂、杀真菌剂、药物或农药）的载体/传递系统。
• US7981436B2
  申请人：——

  公开号：US7981436B2

  公开（公告）日：2011-07-19
• US9744183B2
  申请人：——

  公开号：US9744183B2

  公开（公告）日：2017-08-29
• [EN] METHODS AND COMPOSITIONS OF BIOLOGICALLY ACTIVE AGENTS<br/>[FR] PROCÉDÉS ET COMPOSITIONS D'AGENTS BIOLOGIQUEMENT ACTIFS
  申请人：WAVE LIFE SCIENCES LTD

  公开号：WO2017192679A1

  公开（公告）日：2017-11-09

  In some embodiments, the present disclosure pertains to compositions and methods related to delivery of a biologically active agent, wherein the compositions comprise a biologically active agent and a lipid. In various embodiments, the lipid is selected from: lauric acid, myristic acid, palmitic acid, stearic acid, oleic acid, linoleic acid, alpha-linolenic acid, gamma-linolenic acid, docosahexaenoic acid (cis-DHA), turbinaric acid and dilinoleyl. In some embodiments, a composition and method are useful for delivery of a biologically active agent to a particular cell or tissue, e.g., a muscle cell or tissue.
• [EN] TECHNOLOGIES FOR OLIGONUCLEOTIDE PREPARATION<br/>[FR] TECHNOLOGIES DE PRÉPARATION D'OLIGONUCLÉOTIDES
  申请人：WAVE LIFE SCIENCES LTD

  公开号：WO2019055951A1

  公开（公告）日：2019-03-21

  Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.