General classes of 2-thiazolyl tetrazolium salt compounds have been found to be characterized by a reflectance spectrum exhibiting an extended plateau above about 600-650 nm. Such compounds are useful as chromogenic indicators for reducing substances such as NADH. The reflectance plateau confers improved accuracy to analytical assays, particularly for the determination of analytes of medical diagnostic significance, in which a colorimetric response on a reagent carrier matrix is measured by reflectance.
已发现 2-
噻唑基
四唑盐化合物的一般类别具有反射光谱的特征,即在大约 600-650 纳米波长以上有一个扩展的高原。此类化合物可用作还原性物质(如
NADH)的发色性指示剂。反射高原提高了分析测定的准确性,特别是在测定具有医疗诊断意义的分析物时,其中试剂载体基质上的比色反应是通过反射测定的。