N-4-(dimethylamino)benzamido-N'-1-naphthylurea | 889223-05-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: N-4-(dimethylamino)benzamido-N'-1-naphthylurea
• 英文别名: 1-[[4-(Dimethylamino)benzoyl]amino]-3-naphthalen-1-ylurea
• CAS: 889223-05-6
• 化学式: C₂₀H₂₀N₄O₂
• 分子量: 348.404
• InChiKey: CNDFCLJRBAOSPK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  73.5
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对二甲氨基苯甲酰肼 、 1-Alapha-萘异氰酸酯 以 乙二醇甲醚 为溶剂， 反应 12.0h， 以55%的产率得到N-4-(dimethylamino)benzamido-N'-1-naphthylurea
  参考文献：
  名称：

  An intramolecular charge transfer fluorescent probe: Synthesis and selective fluorescent sensing of Ag+

  摘要：

  An intramolecular charge transfer (ICT) fluorescent probe, in which the thiourea derivative moiety is linked to the fluorescent 4-(dimethylamino) benzamide, has been designed and synthesized. The ions-selective signaling behaviors of the probe were investigated. Upon the addition of Ag+, an overall emission enhancement of 14-fold was observed. Compound I displayed highly selective chelation enhanced fluorescence (CHEF) effect with Ag+ over alkali, alkali earth metal ions and some transition metal ions in aqueous methanol solutions. The prominent selective and efficient fluorescent enhancing behavior could be utilized as a new chemosensing probe for the analysis of Ag+ ion in aqueous environment. (C) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2007.10.006