| 1374301-39-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1374301-39-9
• 化学式: C₂₆H₂₂N₂O₅
• 分子量: 442.471
• InChiKey: SGTIRYNUZWKQQQ-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  1,3-二甲基巴比妥酸 、 5,5-二甲基-1,3-环己二酮 、 苊醌 在 dodecyl benzenesulfonic acid immobilized on silica-coated γ-Fe2O3 nanoparticles 作用下， 以 水 为溶剂， 反应 3.0h， 以91%的产率得到
  参考文献：
  名称：

  One-Pot, Three-Component Synthesis of a Library of Spirooxindole-Pyrimidines Catalyzed by Magnetic Nanoparticle Supported Dodecyl Benzenesulfonic Acid in Aqueous Media

  摘要：

  Dodecyl benzenesulfonic acid functionalized silica-coated magnetic nanoparticles (gamma-Fe2O3@SiO2-DDBSA) were readily prepared and identified as an efficient catalyst for the synthesis of a library of spirooxindole-pyrimidine derivatives by three-component condensation reaction of barbituric acids, isatins and cyclohexane-1,3-diones. The aqueous reaction medium, easy recovery of the catalyst using an external magnet, and high yields make the protocol sustainable and economic.

  DOI：

  10.1021/co3000264