trimethylamine picrate | 7468-01-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: trimethylamine picrate
• 英文别名: picric acid ; trimethylamine picrate；Picrinsaeure; Trimethylamin-picrat；N,N-dimethyl-methanamine, compd. with 2,4,6-trinitrophenol (1:1)；Trimethylammoniumpikrat；trimethylazanium;2,4,6-trinitrophenolate
• CAS: 7468-01-1
• 化学式: C₃H₉N*C₆H₃N₃O₇
• 分子量: 288.217
• InChiKey: CPRJGKJPSMERNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.29
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  161
• 氢给体数：
  1
• 氢受体数：
  8

文献信息

• Marker assisted selection of chicken against fishy taint
  申请人：Lohmann Tierzucht GmbH

  公开号：EP1518936A1

  公开（公告）日：2005-03-30

  The present invention relates to a method of testing an avian for its predisposition for fishy taint in eggs, comprising analyzing the nucleic acid of a sample comprising the gene encoding flavin-containing monooxygenase 3 (FMO3) or a corresponding mRNA for nucleotide polymorphisms which are linked to said predisposition, wherein a difference from the wild-type FMO3 sequence is indicative of fishy taint. The present invention also relates to a method of testing an avian for its predisposition for fishy taint in eggs comprising testing a sample for the presence or absence of a threonine in position 329 of FMO3, wherein an absence of a threonine in said position is indicative for a predisposition to produce fishy tainted eggs or to pass on to the offspring a gene responsible for developing such a phenotype. Finally, the present invention relates to a kit for the detection of animals having a predisposition for fishy taint in eggs, comprising a nucleic acid molecule of wild-type FMO3 or a fragment thereof, or a nucleic acid molecule differing from wild-type FMO3 by at least one polymorphism of the present invention or a fragment of said nucleic acid molecule, or antibodies specific to FMO3, in one or more container.

  本发明涉及一种检测禽类对鸡蛋腥臭的易感性的方法，包括分析包含编码含黄素单氧化酶3（FMO3）的基因或相应mRNA的样品核酸中与所述易感性相关的核苷酸多态性，其中与野生型FMO3序列的差异指示腥臭。本发明还涉及一种禽类腥臭蛋易感性的检测方法，包括检测样品中 FMO3 第 329 位苏氨酸的存在或缺失，其中所述位置上苏氨酸的缺失表明禽类有产生腥臭蛋的易感性，或将产生这种表型的基因遗传给后代。最后，本发明涉及一种用于检测具有鸡蛋腥臭倾向的动物的试剂盒，该试剂盒包含野生型 FMO3 的核酸分子或其片段，或与野生型 FMO3 存在至少一种本发明的多态性差异的核酸分子或所述核酸分子的片段，或特异于 FMO3 的抗体，装在一个或多个容器中。