[4-[4-[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2-hydroxy-3-methoxynaphthalen-1-yl]-3-hydroxy-2-methoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate | 328379-68-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: [4-[4-[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2-hydroxy-3-methoxynaphthalen-1-yl]-3-hydroxy-2-methoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
• CAS: 328379-68-6
• 化学式: C₉₆H₇₈O₁₈
• 分子量: 1519.66
• InChiKey: BFWVQOUYPUQBQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  21.8
• 重原子数：
  114
• 可旋转键数：
  23
• 环数：
  16.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  204
• 氢给体数：
  2
• 氢受体数：
  18

反应信息

• 作为反应物：
  描述：

  [4-[4-[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2-hydroxy-3-methoxynaphthalen-1-yl]-3-hydroxy-2-methoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate 、 碘甲烷 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 2.0h， 以86%的产率得到[4-[4-[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
  参考文献：
  名称：

  Configurationally defined sexi- and octinaphthalene derivatives: synthesis and optical properties

  摘要：

  The copper mediated oxidative coupling of optically active quaternaphthalenes having a 2-hydroxynaphthyl moiety gave configurationally defined optically active octinaphthalenes. The absolute configuration was determined by comparison with products of [6+2] coupling. The CD spectra of bi-, ter-, quater-, sexi- and octinaphthalenes suggested that the absolute configuration of the chiral axis could be deduced from the intensity of their Cotton effects. (C) 2004 Published by Elsevier Ltd.

  DOI：

  10.1016/j.tet.2004.03.055
• 作为产物：
  描述：

  Acetic acid 3'''-hydroxy-2,2',3',2'',3'',2'''-hexamethoxy-[1,1';4',1'';4'',1''']quaternaphthalen-3-yl ester 以14%的产率得到[4-[4-[4-[4-[4-[4-[4-(3-Acetyloxy-2-methoxynaphthalen-1-yl)-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2-hydroxy-3-methoxynaphthalen-1-yl]-3-hydroxy-2-methoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-2,3-dimethoxynaphthalen-1-yl]-3-methoxynaphthalen-2-yl] acetate
  参考文献：
  名称：

  Synthesis of Configurationally Defined Sexi- and Octinaphthalene Derivatives

  摘要：

  [GRAPHICS]Configurationally defined optically active octinaphthalenes were synthesized using the oxidative coupling of optically active quaternaphthalenes with a 2-hydroxynaphthol moiety as a key reaction. The absolute configuration was determined by comparison with products of [6 + 2] coupling.

  DOI：

  10.1021/ol006843c