(E) 5-methoxy-2-methyl-1-(p-methylsulfinylbenzylidene)-3-indenylacetic acid | 142958-43-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 茚和异茚
• 英文名称: (E) 5-methoxy-2-methyl-1-(p-methylsulfinylbenzylidene)-3-indenylacetic acid
• 英文别名: 2-[(3E)-6-methoxy-2-methyl-3-[(4-methylsulfinylphenyl)methylidene]inden-1-yl]acetic acid
• CAS: 142958-43-8
• 化学式: C₂₁H₂₀O₄S
• 分子量: 368.453
• InChiKey: JCWZPYFTBNJDBH-VCHYOVAHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  26
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  82.8
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Method for treating patients with neoplasia by administering substituted sulfonyl indenyl acetic and propionic acids and esters thereof
  申请人：——

  公开号：US20020107248A1

  公开（公告）日：2002-08-08

  Substituted indenyl sulfonyl acetic acids are useful in the treatment of precancerous lesions.

  取代的茚基磺酰乙酸在治疗癌前病变方面是有用的。
• Resin composition for sealing electronic parts, and hydration-resistant magnesia powder and process for preparation thereof
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0209847A2

  公开（公告）日：1987-01-28

  Disclosed is a resin composition for sealing electronic parts, which comprises a thermosetting resin and, incorporated therein, high-purity magnesium oxide. A hydration-resistant magnesia powder having the particle surfaces covered with a continuous and uniform coating of silica is advantageously used as the magnesium oxide. This hydration-resistant magnesia powder is prepared by introducing a heated vapor of an organic silicate compound into a reactor of a fluidized bed of magnesia powder heated at 100 to 600°C so that the concentration of the organic silicate compound is 1 to 20 mole%, and precipitating a coating of silica on the surfaces of magnesia particles by thermal decomposition and/or hydrolysis of the organic silicate compound on the surfaces of magnesia particles.

  本发明公开了一种用于密封电子部件的树脂组合物，该组合物由热固性树脂和掺入其中的高纯度氧化镁组成。 使用颗粒表面覆盖有一层连续均匀的二氧化硅涂层的抗水化菱镁粉末作为氧化镁具有优势。 这种抗水化菱镁粉末的制备方法是：将有机硅酸盐化合物的加热蒸汽引入在 100 至 600°C 下加热的菱镁粉末流化床反应器中，使有机硅酸盐化合物的浓度为 1 至 20 摩尔%，并通过菱镁颗粒表面的有机硅酸盐化合物的热分解和/或水解作用在菱镁颗粒表面析出二氧化硅涂层。
• Process for preparation of cured resin molded article and reactive curable molding composition used therefor
  申请人：TEIJIN LIMITED

  公开号：EP0338694A2

  公开（公告）日：1989-10-25

  A cured resin molded article is prepared by forming independently [I] a liquid composition consisting essentially of an unsaturated polyester and a polyfunctional epoxide and [II] a liquid composition consisting essentially of an amine type epoxy-curing agent and a vinyl-polymerizable reactive diluent, incorporating a radical initiator into at least one of the two liquid compositions before or at the molding step, mixing both liquid compositions at the molding step, and reacting and curing the mixture.

  制备固化树脂模塑件的方法是：[I] 分别形成主要由不饱和聚酯和多官能环氧化物组成的液态组合物，[II] 形成主要由胺类环氧固化剂和乙烯基可聚合反应稀释剂组成的液态组合物，在模塑步骤之前或模塑步骤中将自由基引发剂加入这两种液态组合物中的至少一种，在模塑步骤中混合这两种液态组合物，并对混合物进行反应和固化。
• Epoxy resin compositions containing highly transparent silica-titania glass beads
  申请人：SHIN-ETSU CHEMICAL CO., LTD.

  公开号：EP0441622A1

  公开（公告）日：1991-08-14

  High transparency silica-titania glass beads are characterized by a linear transmittance of at least 70% as measured at a wavelength of 900 nm to 600 nm by a specific measurement method. Such beads are prepared by hydrolyzing and polycondensing a silicon alkoxide and a titanium alkoxide to form a silica-titania sol, converting the sol into a dry gel, and then grinding the gel followed by heating or heating the gel followed by grinding. A light transmission epoxy resin composition comprising a curable epoxy resin, a curing agent, and the high transparency silica-titania glass beads has crack resistance and high transparency in cured state. It is useful in encapsulating optical semiconductor devices.

  高透明度硅钛玻璃珠的特点是，通过特定的测量方法，在波长为 900 纳米至 600 纳米时，线性透射率至少为 70%。这种微珠的制备方法是：将硅烷氧基化合物和钛烷氧基化合物水解和缩聚形成硅钛溶胶，将溶胶转化为干凝胶，然后研磨凝胶并加热或加热凝胶并研磨。由可固化环氧树脂、固化剂和高透明度硅钛玻璃微珠组成的透光环氧树脂组合物在固化状态下具有抗裂性和高透明度。它可用于封装光学半导体器件。
• Hydration-resistant magnesia powder and process for preparation thereof
  申请人：UBE INDUSTRIES, LTD.

  公开号：EP0476709A2

  公开（公告）日：1992-03-25

  Disclosed is a hydration-resistant magnesia powder having the particle surfaces covered with a continuous and uniform coating of silica. This hydration-resistant magnesia powder is prepared by introducing a heated vapor of an organic silicate compound into a reactor of a fluidized bed of magnesia powder heated at 100 to 600°C so that the concentration of the organic silicate compound is 1 to 20 mole%, and precipitating a coating of silica on the surfaces of magnesia particles by thermal decomposition and/or hydrolysis of the organic silicate compound on the surfaces of magnesia particles. The new hydration-resistant magnesia powder is highly useful for preparing resin composition for sealing electronic parts.

  本发明公开了一种耐水合氧化镁粉末，其颗粒表面覆盖有一层连续均匀的二氧化硅涂层。这种耐水合氧化镁粉末的制备方法是：将有机硅酸盐化合物的加热蒸汽引入在 100 至 600°C 下加热的氧化镁粉末流化床反应器中，使有机硅酸盐化合物的浓度为 1 至 20 摩尔%，然后通过氧化镁颗粒表面的有机硅酸盐化合物的热分解和/或水解，在氧化镁颗粒表面析出二氧化硅涂层。新的耐水合氧化镁粉末非常适用于制备用于密封电子部件的树脂组合物。