Octahydro-4,7-methano-inden-1-ylamine | 32233-93-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: Octahydro-4,7-methano-inden-1-ylamine
• 英文别名: Tricyclo[5.2.1.02,6]decan-3-amine
• CAS: 32233-93-5
• 化学式: C₁₀H₁₇N
• 分子量: 151.252
• InChiKey: XEIKUZBPQQHKCG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  26
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Substituted heterocyclo-norbornylamino derivatives, processes for their preparation, their use as medicaments or diagnostics, and medicaments comprising them
  申请人：——

  公开号：US20020173500A1

  公开（公告）日：2002-11-21

  Substituted heterocyclo-norbornylaminoderivatives having: a) an exo-configuration nitrogen and an endo-fused five-membered ring or six-membered ring of the formula (I) or b) an exo-configuration nitrogen and an exo-fused five-membered ring or six-membered ring of the formula (Ia), 1 wherein R n , Het, A, B and T have the meanings given in the claims. These compounds have a variety of uses. They can be used as antihypertensives, for the reduction or prevention of is chemically induced damage, as pharmaceuticals for surgical interventions, for the treatment of ischemia of the nervous system, including stroke and cerebral edema, for the treatment of ischemia due to shock and disturbed respiratory drive, for the treatment of snoring, as a laxative, as an agent against ectoparasites, for the prevention of gallstone formation, as an antiatherosclerotic, as an agent against diabetic late complications, cancers, fibrotic disorders, endothelial dysfunction, organ hypertrophy, and organ hyperplasia. The compounds of the invention are inhibitors of the cellular sodium-proton antiporter. Additonally, the compounds of the invention influence the serum lipoproteins and can therefore be used for the prophylaxis and the regression of atherosclerotic changes.

  具有以下结构的取代杂环-去氢萘基氨基衍生物：a）具有外向构型的氮和内向融合的五元环或六元环的式（I）或b）具有外向构型的氮和外向融合的五元环或六元环的式（Ia），其中Rn，Het，A，B和T具有权利要求中给出的含义。这些化合物具有各种用途。它们可以用作降压药，用于减少或预防化学诱导的损伤，作为手术干预的药物，用于治疗神经系统缺血，包括中风和脑水肿，用于治疗休克和呼吸驱动障碍引起的缺血，用于治疗打鼾，作为泻药，用作抗外寄生虫剂，用于预防胆结石形成，作为抗动脉粥样硬化药物，用作抗糖尿病晚期并发症、癌症、纤维化疾病、内皮功能障碍、器官肥大和器官增生的药物。本发明化合物是细胞钠-质子抗运输蛋白的抑制剂。此外，本发明化合物影响血清脂蛋白，因此可用于动脉粥样硬化变化的预防和回归。
• THERMOSETTING RESIN COMPOSITION
  申请人：DIC Corporation

  公开号：EP1964869A1

  公开（公告）日：2008-09-03

  The object of the present invention is to provide a thermosetting resin composition which can provide a cured material which is excellent in heat resistance, electrical properties, and flexibility, and has storage stability before curing, and in order to achieve the object, the present invention provide a thermosetting resin composition containing a polyurethane resin (A) which has the structure represented by the following general formula (1) and/or the general formula (2), and an epoxy resin (B). (In the chemical formulae, X represents a residue in which two phenolic hydroxyl groups are excluded from a phenol compound having two or more phenolic hydroxyl groups in the molecule.)

  本发明的目的是提供一种热固性树脂组合物，该组合物可以提供耐热性、电性能和柔韧性优异的固化材料，并且在固化前具有贮存稳定性，为了实现该目的，本发明提供了一种热固性树脂组合物，该组合物包含具有以下通式（1）和/或通式（2）所代表结构的聚氨酯树脂（A）和环氧树脂（B）。 (在化学式中，X 代表分子中有两个或两个以上酚羟基的苯酚化合物中排除了两个酚羟基的残基)。
• US6737423B2
  申请人：——

  公开号：US6737423B2

  公开（公告）日：2004-05-18