2-(1-ethylpropylamino)ethanol hydrochloride | 610309-68-7

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-(1-ethylpropylamino)ethanol hydrochloride
• 英文别名: 2-Hydroxyethyl(pentan-3-yl)azanium;chloride
• CAS: 610309-68-7
• 化学式: C₇H₁₇NO*ClH
• 分子量: 167.679
• InChiKey: RWQDTINQZYHQEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.18
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  36.8
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• Kappa-opioid receptor agonist comprising 2-phenylbenzothiazoline derivative
  申请人：Tokai Maki

  公开号：US20050113430A1

  公开（公告）日：2005-05-26

  The present invention provides κ opioid receptor agonists comprising 2-phenylbenzothiazoline derivatives. The present invention relates to κ opioid receptor agonists comprising compounds or salts thereof having the chemical structure represented by the general formula [I]. Namely, it is important for exhibition of the κ opioid receptor agonist actions to have an alkyl group having an amino group at a phenyl group of 2-phenylbenzothiazoline as a substituent and to have an acyl group at a nitrogen atom of 2-phenylbenzothiazoline, wherein R is alkyl having the amino group as the substituent; and R 1 is acyl.

  本发明提供了包含2-苯基苯并噻唑衍生物的κ阿片受体激动剂。本发明涉及化学结构式[I]所表示的化合物或其盐，其包含κ阿片受体激动剂，即在2-苯基苯并噻唑的苯基上具有氨基取代基的烷基取代基，并在2-苯基苯并噻唑的氮原子上具有酰基取代基，这对于展示κ阿片受体激动剂作用非常重要，其中R是具有氨基取代基的烷基取代基；R1是酰基。
• Method for treating pain or pruritis by administering opinoid receptor agonist comprising 2-phenylbenzothiazoling derivative
  申请人：Tokai Maki

  公开号：US20060205796A1

  公开（公告）日：2006-09-14

  A method of treating pain or pruritis comprising administering to a patient in need thereof a pharmaceutically effective amount of a κ opioid receptor agonist of the formula wherein R is an alkyl having an amino group as a substituent; and R 1 is acyl.

  一种治疗疼痛或瘙痒的方法，包括向需要治疗的患者给予药效有效量的κ阿片受体激动剂，该激动剂的化学式为其中R是具有氨基基团的烷基；R1是酰基。
• KAPPA-OPIOID RECEPTOR AGONIST COMPRISING 2-PHENYLBENZOTHIAZOLINE DERIVATIVE
  申请人：SANTEN PHARMACEUTICAL CO., LTD.

  公开号：EP1496053A1

  公开（公告）日：2005-01-12

  The present invention provides κ opioid receptor agonists comprising 2-phenylbenzothiazoline derivatives. The present invention relates to κ opioid receptor agonists comprising compounds or salts thereof having the chemical structure represented by the general formula [I]. Namely, it is important for exhibition of the κ opioid receptor agonist actions to have an alkyl group having an amino group at a phenyl group of 2-phenylbenzothiazoline as a substituent and to have an acyl group at a nitrogen atom of 2-phenylbenzothiazoline, wherein R is alkyl having the amino group as the substituent; and R1 is acyl.

  本发明提供了由 2-苯基苯并噻唑啉衍生物组成的 κ 阿片受体激动剂。本发明涉及由具有通式[I]所代表的化学结构的化合物或其盐组成的κ阿片受体激动剂。也就是说，对于展示κ阿片受体激动剂的作用而言，重要的是在 2-苯基苯并噻唑啉的苯基上具有氨基的烷基作为取代基，并且在 2-苯基苯并噻唑啉的氮原子上具有酰基、 其中 R 是以氨基为取代基的烷基；R1 是酰基。
• Cleaning composition with di(fatty acyloxyalkyl)hydroxyalkyl alkylammonium quaternary salt or alkyl trimethyl ammonium fatty alkanoate ionic liquids
  申请人：S.C. Johnson & Son, Inc.

  公开号：US10179890B2

  公开（公告）日：2019-01-15

  An aqueous cleaning composition, which may be suitable for use in cleaning hard surfaces, is described. The aqueous cleaning composition includes an ionic liquid solvent, an amino alcohol, and a substantial amount of water. The cleaning compositions may also include a disinfecting quaternary surfactant, a nonionic surfactant, such as an ethoxylated alcohol and/or alkyl polyglycoside, and/or a chelating agent, such as an aminopolycarboxylate chelating agent.

  本文介绍了一种适用于清洁硬表面的水性清洁组合物。水性清洁组合物包括离子液体溶剂、氨基醇和大量的水。清洁组合物还可包括消毒季表面活性剂、非离子表面活性剂（如乙氧基化醇和/或烷基多糖苷）和/或螯合剂（如氨基多羧酸盐螯合剂）。
• Cleaning composition with an N-alkyl-N,N-dipolyethoxyethyl-N-alkylammonium salt ionic liquid
  申请人：S.C. Johnson & Son, Inc.

  公开号：US10988711B2

  公开（公告）日：2021-04-27

  An aqueous cleaning composition, which may be suitable for use in cleaning hard surfaces, is described. The aqueous cleaning composition includes an ionic liquid solvent, an amino alcohol, and a substantial amount of water. The cleaning compositions may also include a disinfecting quaternary surfactant, a nonionic surfactant, such as an ethoxylated alcohol and/or alkyl polyglycoside, and/or a chelating agent, such as an aminopolycarboxylate chelating agent.

  本文介绍了一种适用于清洁硬表面的水性清洁组合物。水性清洁组合物包括离子液体溶剂、氨基醇和大量的水。清洁组合物还可包括消毒季表面活性剂、非离子表面活性剂（如乙氧基化醇和/或烷基多糖苷）和/或螯合剂（如氨基多羧酸盐螯合剂）。