2-Dimethylamino-4-methyl-penten-(1) | 20984-02-5

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 2-Dimethylamino-4-methyl-penten-(1)
• 英文别名: N,N,4-trimethylpent-1-en-2-amine
• CAS: 20984-02-5
• 化学式: C₈H₁₇N
• 分子量: 127.23
• InChiKey: CFXVDCKMOWZESU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• BRIDGED HETEROCYCLIC COMPOUNDS AND METHODS OF USE
  申请人：MEDIVATION TECHNOLOGIES, INC.

  公开号：US20130190303A1

  公开（公告）日：2013-07-25

  This disclosure relates to new compounds that may be used to modulate a histamine receptor in an individual. Novel compounds are described, including new bridged heterocyclic [4,3-b]indole compounds. Pharmaceutical compositions are also provided. Pharmaceutical compositions comprising the compounds are also provided, as are methods of using the compounds in a variety of therapeutic applications, including the treatment of a cognitive disorder, psychotic disorder, neurotransmitter-mediated disorder and/or a neuronal disorder.

  本公开涉及可用于调节组织胺受体的新化合物。其中描述了新的桥接杂环[4,3-b]吲哚化合物。还提供了制药组合物，包括含有该化合物的制药组合物。还提供了使用该化合物进行各种治疗应用的方法，包括治疗认知障碍、精神障碍、神经递质介导的障碍和/或神经元障碍。
• VIRAL POLYMERASE INHIBITORS
  申请人：Beaulieu Pierre

  公开号：US20120101091A1

  公开（公告）日：2012-04-26

  The present application provides compounds of formula I wherein X, Y, R 2 , n, R 5 and R 6 are defined herein, useful as inhibitors of the hepatitis C virus NS5B polymerase The present application also provides pharmaceutical compositions containing said compounds, methods of using said compounds as pharmaceuticals alone or with other antiviral agent in the treatment of a hepatitis C viral infection in a mammal having or at risk of having the infection.
• US8999977B2
  申请人：——

  公开号：US8999977B2

  公开（公告）日：2015-04-07
• US9193728B2
  申请人：——

  公开号：US9193728B2

  公开（公告）日：2015-11-24
• US9981959B2
  申请人：——

  公开号：US9981959B2

  公开（公告）日：2018-05-29