| 1158868-60-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• CAS: 1158868-60-0
• 化学式: C₅₄H₄₂I₄O₈
• 分子量: 1326.54
• InChiKey: JRHXAUYURXTDRL-UHFFFAOYSA-N

物化性质

• 熔点：
  247-249 °C
• 密度：
  1.738±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  15.32
• 重原子数：
  66.0
• 可旋转键数：
  16.0
• 环数：
  9.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  73.84
• 氢给体数：
  0.0
• 氢受体数：
  8.0

反应信息

• 作为反应物：
  描述：

  在 盐酸 、 水 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 4.0h， 以99%的产率得到6-[4-[6-Hydroxy-5-(2-hydroxy-3-iodonaphthalen-1-yl)-7-iodonaphthalen-2-yl]phenyl]-1-(2-hydroxy-3-iodonaphthalen-1-yl)-3-iodonaphthalen-2-ol
  参考文献：
  名称：

  Self-supported BINOL–Zn catalysts for heterogeneous enantioselective epoxidation of (E)-α,β-unsaturated ketones

  摘要：

  A class of chiral self-supported catalysts prepared from bis-BINOL ligands and diethyl zinc were successfully applied in the hetereogeneous enantioselective epoxidation of a range of (E)-alpha,beta-unsaturated ketones, affording the corresponding epoxy ketones in high enantioselectivity. The self-supported catalysts were easily recovered from the reaction mixture and were reusable for several consecutive runs. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.151
• 作为产物：
  描述：

  在 正丁基锂 、 碘 作用下， 以 四氢呋喃 、 乙醚 、 正己烷 为溶剂， 以43%的产率得到
  参考文献：
  名称：

  Self-supported BINOL–Zn catalysts for heterogeneous enantioselective epoxidation of (E)-α,β-unsaturated ketones

  摘要：

  A class of chiral self-supported catalysts prepared from bis-BINOL ligands and diethyl zinc were successfully applied in the hetereogeneous enantioselective epoxidation of a range of (E)-alpha,beta-unsaturated ketones, affording the corresponding epoxy ketones in high enantioselectivity. The self-supported catalysts were easily recovered from the reaction mixture and were reusable for several consecutive runs. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2009.02.151