2-chloro-6-(7-(2-((3-chloro-2-hydroxybenzylidene)amino)ethyl)-3,3-dimethoxy-2-oxa-7,10-diaza-3-silaundec-10-en-11-yl)phenol | 1254322-81-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2-chloro-6-(7-(2-((3-chloro-2-hydroxybenzylidene)amino)ethyl)-3,3-dimethoxy-2-oxa-7,10-diaza-3-silaundec-10-en-11-yl)phenol
• CAS: 1254322-81-0
• 化学式: C₂₄H₃₃Cl₂N₃O₅Si
• 分子量: 542.535
• InChiKey: NIKKEFSMISMKTB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.51
• 重原子数：
  35.0
• 可旋转键数：
  15.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  96.11
• 氢给体数：
  2.0
• 氢受体数：
  8.0

反应信息

• 作为产物：
  描述：

  6,6'-(((azanediylbis(ethane-2,1-diyl))bis(azaneylylidene))bis(methaneylylidene))bis(2-chlorophenol) 、 3-碘苯基三甲氧基硅烷 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 反应 22.0h， 以90%的产率得到2-chloro-6-(7-(2-((3-chloro-2-hydroxybenzylidene)amino)ethyl)-3,3-dimethoxy-2-oxa-7,10-diaza-3-silaundec-10-en-11-yl)phenol
  参考文献：
  名称：

  Novel alkoxysilane pentacoordinate OV(IV) complexes as supported catalysts for cyclohexane oxidation with dioxygen

  摘要：

  A variety of newly synthesized and well characterized alkoxysilane pentacoordinate Oxovanadium(IV) complexes, VO[Sal(PMeOSi)DPTA] 3[a], VOICI-Sal(PMeOSi)DPTAI 3[b], VO[Sal(PMeOSi)DETA] 6[a] and VO[Cl-Sal(PMeOSi)DETA] OA, (Sal = salicylaldehyde, DPTA= bis(aminopropyl)amine, DETA = diaminoethylamine), have been anchored by covalent bond into the surface of SiO(2) and/or Al(2)O(3) via silicon-alkoxide route by a condensation process as supported catalysts. These solid supported catalysts (abbreviated as catalysts A to H) showed high catalytic efficiency in the selective oxidation reaction of cyclohexane using molecular oxygen under relatively mild condition in a micro-batch reactor. The Catalyst C (SiO(2)/3[a] complex) system exhibits best activity, overall yield 38.5% (TONs, ca. 5.0 x 10(3)) as well as high selectivity 98% (cyclohexanol 74%, cyclohexanone 24%). Notably, cyclohexane shows significantly improved yield 44.0%, by the addition of pyrazinecarboxylic acid as a co-catalyst. The TGA indicates these catalysts are stable up to maximum reaction temperature, ca. 473 K and ICP analysis shows there is negligible vanadium loss from the supported catalyst after the reaction, allowing further use of the V-catalyst. The various factors influences (i.e. temperature, O(2) pressure, reaction time, catalyst amount) were also investigated in the systematic way, to optimize the reaction processes. The impact of radical traps and detection of intermediate peroxy radical were also investigated to establish a radical mechanism. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.apcata.2010.06.018