(S)-5-Hydroxy-nonanoic acid ((S)-1-naphthalen-1-yl-ethyl)-amide | 483287-65-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: (S)-5-Hydroxy-nonanoic acid ((S)-1-naphthalen-1-yl-ethyl)-amide
• CAS: 483287-65-6
• 化学式: C₂₁H₂₉NO₂
• 分子量: 327.467
• InChiKey: PUUSNAVBUQGQJQ-WMZOPIPTSA-N

物化性质

• 沸点：
  544.4±43.0 °C(Predicted)
• 密度：
  1.058±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.74
• 重原子数：
  24.0
• 可旋转键数：
  9.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.48
• 拓扑面积：
  49.33
• 氢给体数：
  2.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  (S)-5-Hydroxy-nonanoic acid ((S)-1-naphthalen-1-yl-ethyl)-amide 在 盐酸 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  Optical Resolution of Fragrant Lactones

  摘要：

  Optical resolution of six chiral fragrant lactones (delta-jasmine lactone, massoia lactone, tuberolactone, pentynyllactone, delta-decalactone, and gamma-nonalactone) was investigated by means of either the diastereomeric salt formation method or the diastereomeric amide formation method. Using these procedures, we obtained each enantiomer from five of the six lactones, except for massoia lactone. All five lactones were obtained in a good yield and with high optical purity. Sensoric characteristics on both enantiomers and racemic modification of four lactones are given.

  DOI：

  10.3987/com-99-s149
• 作为产物：
  描述：

  (S)-(-)-1-(1-萘基)乙胺 、 γ-壬内酯 以 甲苯 为溶剂， 以30.2%的产率得到(S)-5-Hydroxy-nonanoic acid ((S)-1-naphthalen-1-yl-ethyl)-amide
  参考文献：
  名称：

  Optical Resolution of Fragrant Lactones

  摘要：

  Optical resolution of six chiral fragrant lactones (delta-jasmine lactone, massoia lactone, tuberolactone, pentynyllactone, delta-decalactone, and gamma-nonalactone) was investigated by means of either the diastereomeric salt formation method or the diastereomeric amide formation method. Using these procedures, we obtained each enantiomer from five of the six lactones, except for massoia lactone. All five lactones were obtained in a good yield and with high optical purity. Sensoric characteristics on both enantiomers and racemic modification of four lactones are given.

  DOI：

  10.3987/com-99-s149