5.6-dinitro-o-cresol | 70637-65-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 5.6-dinitro-o-cresol
• 英文别名: 5.6-Dinitro-o-kresol；3.4-Dinitro-2-oxy-toluol；Dinitrohydroxytoluene；6-methyl-2,3-dinitrophenol
• CAS: 70637-65-9
• 化学式: C₇H₆N₂O₅
• 分子量: 198.135
• InChiKey: ZJZCICWBZBAUQT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  112
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 nitrogen oxides 、 硫酸 作用下， 生成 5.6-dinitro-o-cresol
  参考文献：
  名称：

  Datta; Varma, Journal of the American Chemical Society, 1919, vol. 41, p. 2041

  摘要：

  DOI：

文献信息

• [EN] FUEL COMPOSITIONS COMPRISING ISOPRENE DERIVATIVES<br/>[FR] COMPOSITIONS DE CARBURANT CONTENANT DES DÉRIVÉS D'ISOPRÈNE
  申请人：DANISCO US INC

  公开号：WO2011160081A1

  公开（公告）日：2011-12-22

  The invention provides for methods, compositions and systems using isoprene from a bioisoprene composition derived from renewable carbon for production of a variety of hydrocarbon fuels, fuel additives, and additives for fine chemistry and other uses.

  这项发明提供了利用从可再生碳源衍生的生物异戊二烯组合物中提取异戊二烯的方法、组合物和系统，用于生产各种烃燃料、燃料添加剂以及精细化学和其他用途的添加剂。
• Physical, chemical, and isotopic (atomic) labels
  申请人：Pearl Technology Holdings, LLC.

  公开号：US20040258617A1

  公开（公告）日：2004-12-23

  Chemical or isotopic labels are added to, e.g., a potentially lethal drug formulation, to generate a unique chemical fingerprint. Combinations of chemical additives are mixed with the drug to aid in their isolation and identification, especially when such drugs are used for illicit purposes. When stable isotopes are incorporated into lethal drugs, the labeling process conveys a very unique internal chemical signature and greatly aids in the identification of the parent drug in body fluids and tissues. When heath-care providers become aware that certain drugs can now be easily tracked and identified in a victim, individuals may be reluctant to utilize these agents for ill purposes.

  化学或同位素标记被添加到例如潜在致命的药物配方中，以生成独特的化学指纹。化学添加剂的组合与药物混合在一起，以帮助其隔离和识别，尤其是当这些药物被用于非法目的时。当稳定同位素被纳入致命药物中时，标记过程传达了非常独特的内部化学签名，并极大地帮助在体液和组织中识别母药。当医疗保健提供者意识到某些药物现在可以轻松跟踪和识别受害者时，个人可能会不愿意将这些药物用于不良目的。
• NICOTINYL RIBOSIDE COMPOUNDS AND THEIR USES
  申请人：MitoPower, LLC

  公开号：US20200397807A1

  公开（公告）日：2020-12-24

  The disclosure provides nicotinamide riboside (NR), the reduced form of NR (NRH), nicotinic acid riboside (NAR), the reduced form of NAR (NARH), derivatives thereof, compositions thereof and uses thereof. The NR and NAR derivatives have improved stability and bioavailability compared to NR and NAR. NR, NRH, NAR, NARH, and derivatives thereof can increase cellular NAD + levels and enhance mitochondrial and cellular function and cell viability. Therefore, NR, NRH, NAR, NARH, and derivatives thereof, whether alone or in combination with one or more additional therapeutic agents (e.g., a mitochondrial uncoupler or/and a PARP inhibitor), are useful for treating mitochondrial diseases, mitochondria-related diseases and conditions, metabolic disorders, and other disorders and conditions.

  该披露提供烟酰胺核糖苷（NR）、烟酰胺核糖苷的还原形式（NRH）、烟酸核糖苷（NAR）、烟酸核糖苷的还原形式（NARH）、以及它们的衍生物、组合物和用途。与NR和NAR相比，NR和NAR的衍生物具有更好的稳定性和生物利用度。NR、NRH、NAR、NARH和它们的衍生物可以增加细胞NAD+水平，增强线粒体和细胞功能以及细胞存活能力。因此，NR、NRH、NAR、NARH和它们的衍生物，无论是单独使用还是与一个或多个额外治疗剂（例如线粒体解耦蛋白抑制剂和/或PARP抑制剂）结合使用，都可用于治疗线粒体疾病、与线粒体相关的疾病和症状、代谢紊乱以及其他疾病和症状。
• Method for extracting nitrocresols from waste water produced in the manufacture of mononitrotoluene and use of said extract
  申请人：Buettner Johannes

  公开号：US20070043244A1

  公开（公告）日：2007-02-22

  The invention provides a process for removing nitrocresols from wastewater of mononitrotoluene preparation, which comprises acidifying the alkaline wastewater of mononitrotoluene preparation with acids to a pH of at most 3 and treating the nitrocresols with an extractant. The invention further provides the preparation of dinitrotoluene by use of the nitrocresol-containing extracts as a feedstock.

  该发明提供了一种从单硝基甲苯制备废水中去除硝基甲酚的方法，包括通过用酸将单硝基甲苯制备的碱性废水酸化至最多3的pH值，并用萃取剂处理硝基甲酚。该发明还提供了利用含硝基甲酚的提取物作为原料生产二硝基甲苯的方法。
• METHOD FOR REMOVING HCN FROM CRUDE DINITRO TOLUENE
  申请人：BASF SE

  公开号：US20160194270A1

  公开（公告）日：2016-07-07

  A process for the preparation of dintrotoluene which comprises (a) nitrating toluene with a nitrating acid, wherein said nitrating acid is a mixture of nitric acid and sulfuric acid, in one or more nitration steps, and separating the nitrating acid from the process stream thus formed, wherein a crude mixture comprising dinitrotoluene and a fraction of said nitrating acid dissolved therein is obtained, said crude mixture further comprising at least 50 ppm of HCN, and (b) washing the crude dinitrotoluene containing mixture in one or more washing steps, wherein, before the first washing step is carried out, the crude mixture is distilled and/or stripped to remove HCN therefrom, wherein a crude dinitrotoluene containing mixture which is essentially free of HCN is obtained.

  一种制备二硝基甲苯的方法，包括（a）用硝化酸对甲苯进行硝化，其中所述硝化酸是硝酸和硫酸的混合物，在一个或多个硝化步骤中进行，并从形成的工艺流中分离出硝化酸，得到包含二硝基甲苯和其中溶解的部分硝化酸的原始混合物，所述原始混合物还包括至少50 ppm的HCN，（b）在一个或多个洗涤步骤中洗涤含有粗二硝基甲苯的混合物，在进行第一次洗涤步骤之前，将粗混合物蒸馏和/或脱除其中的HCN，得到基本上不含HCN的粗二硝基甲苯混合物。