cyclic di-adenosine monophosphate | 952715-25-2

• 分子结构分类: 有机化合物 - 核苷、核苷酸和类似物 - 嘌呤核苷酸
• 英文名称: cyclic di-adenosine monophosphate
• 英文别名: (1S,6S,8S,9S,10R,15R,17R,18R)-8,17-bis(6-aminopurin-9-yl)-3,12-dihydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecane-9,18-diol；(1S,6S,8S,9S,10R,15R,17R,18R)-8,17-bis(6-aminopurin-9-yl)-3,12-dihydroxy-3,12-dioxo-2,4,7,11,13,16-hexaoxa-3λ5,12λ5-diphosphatricyclo[13.3.0.06,10]octadecane-9,18-diol
• CAS: 952715-25-2
• 化学式: C₂₀H₂₄N₁₀O₁₂P₂
• 分子量: 658.418
• InChiKey: PDXMFTWFFKBFIN-WGIMJHEJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -5.1
• 重原子数：
  44
• 可旋转键数：
  2
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  310
• 氢给体数：
  6
• 氢受体数：
  20

反应信息

• 作为产物：
  描述：

  adenosine 5'-phosphorimidazolide 在 咪唑 、 calf intestine alkaline phosphatase 作用下， 以 水 为溶剂， 反应 10.0h， 生成 环二腺苷酸 、 adenylyl-2',5'-adenosine 、 cyclic di-adenosine monophosphate 、
  参考文献：
  名称：

  Regio- and Diastereo-Selectivity of Montmorillonite-Catalyzed Oligomerization of Racemic Adenosine 5′-Phosphorimidazolide

  摘要：

  Clay is a possible candidate for an effective catalyst in prebiotic chemical evolution of biomolecules. Montmorillonite was reported to effectively catalyze oligomerization of racemic adenosine 5'-phosphorimidazolide (DL-ImpA). In the oligomerization reaction, considerable amounts of cyclic dimers as well as linear dimers were produced in the oligomerization reactions. To assess the regio- and diastereo-selectivities of the oligomerization reaction, the dimer products including cyclic dimers were completely identified by means of enzymatic degradation reactions of the products.

  DOI：

  10.1080/15257770801954955