(3-Hydroxy-2,4-dimethyl-phenyl)-acetic acid | 21354-71-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (3-Hydroxy-2,4-dimethyl-phenyl)-acetic acid
• 英文别名: 2-(3-Hydroxy-2,4-dimethylphenyl)acetic acid
• CAS: 21354-71-2
• 化学式: C₁₀H₁₂O₃
• 分子量: 180.203
• InChiKey: MEKADJCCWNRNBX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• EP1339864A4
  申请人：——

  公开号：EP1339864A4

  公开（公告）日：2005-01-12
• PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS
  申请人：Albany Molecular Research, Inc.

  公开号：EP1339864A2

  公开（公告）日：2003-09-03
• [EN] PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS<br/>[FR] PROCEDE DE PRODUCTION DE DERIVES DE PIPERIDINE AVEC DES MICRO-ORGANISMES
  申请人：ALBANY MOLECULAR RES INC

  公开号：WO2002083062A2

  公开（公告）日：2002-10-24

  The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R?1 and R2¿ taken together form a second bond between the carbon atoms bearing R?1 and R2¿, provided that when n is 1, R?1 and R2¿ are each hydrogen; R3 is -COOH or -COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB wherein R3 is -CH¿3? and R?1, R2¿, A, B, and D are defined above. In the presence of a microorganism under conditions effective to produce the product compound. The microorganism can be from the genus Streptomyces, Stemphylium, Gliocladium, Bacillus, Botrytis, Cyathus, Rhizopus, Pycniodosphora, Psuedomonas, Helicostylum, Aspergillus, Mucor, Gelasinospora, Rhodotorula, Candida, Mycobacterium, or Pennicillium. Alternatively, the microorganism can be Cunninghamella bainieri.