tert-Butyl-methyl-(1-methyl-butyl)-amine | 91013-93-3

• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: tert-Butyl-methyl-(1-methyl-butyl)-amine
• 英文别名: N-tert-butyl-N-methylpentan-2-amine
• CAS: 91013-93-3
• 化学式: C₁₀H₂₃N
• 分子量: 157.299
• InChiKey: MRKCQNRYHYBXFO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  3.2
• 氢给体数：
  0
• 氢受体数：
  1

文献信息

• RSV antiviral pyrazolo- and triazolo-pyrimidine compounds
  申请人：Janssen Sciences Ireland UC

  公开号：US10208048B2

  公开（公告）日：2019-02-19

  The invention concerns novel substituted pyrazolo- and triazolo-pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection.

  本发明涉及具有抗病毒活性，特别是对呼吸道合胞病毒（RSV）的复制具有抑制活性的新型取代式吡唑和三唑并嘧啶化合物。本发明还涉及包含这些化合物的药物组合物以及用于治疗呼吸道合胞病毒感染的化合物。
• RSV ANTIVIRAL PYRAZOLO- AND TRIAZOLO-PYRIMIDINE COMPOUNDS
  申请人：Janssen Sciences Ireland UC

  公开号：US20180105529A1

  公开（公告）日：2018-04-19

  The invention concerns novel substituted pyrazolo- and triazolo-pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection.
• NOVEL TRITERPENE DERIVATIVES AS HIV INHIBITORS
  申请人：HETERO LABS LIMITED

  公开号：US20220177439A1

  公开（公告）日：2022-06-09

  The present invention relates to novel triterpene derivatives of formula (I); and pharmaceutically acceptable salts thereof, wherein R 1 , R 2 , R 3 , R 4 , and ring are as defined herein. The invention also relates to novel triterpene derivatives, related compounds, and pharmaceutical compositions useful for the therapeutic treatment of viral diseases and particularly HIV mediated diseases.
• US9689035B2
  申请人：——

  公开号：US9689035B2

  公开（公告）日：2017-06-27
• US9938236B2
  申请人：——

  公开号：US9938236B2

  公开（公告）日：2018-04-10